Formal lodgement of FDA submission for EchoSolv HF

▪ Submission incorporates results of successful clinical validation study with Mayo Clinic Platform’s validation capabilities on an independent dataset of 17,000 individual patient echocardiograms ▪ FDA clearance of EchoSolv HF unlocks a significant opportunity in the US:* o Only 50% of heart failure cases are accurately diagnosed o Estimated that 1 in 4 Americans will develop heart failure in the