Appendix 4D and Half Year Report for period 31 Dec 2025

This half‑year report should be read in conjunction with the Company’s 2025 Annual Report. Note: The financial figures provided are in Australian dollars. 2. Results for announcement to the market The condensed consolidated results of Opthea Limited for the six months ended 31 December 2025 are as follows: An explanation of the figures reported above are contained in the Directors’ Report under th