Stock listing
NASDAQ:SYRE Spyre Therapeutics, Inc. Stock
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Share price · NASDAQ:SYRE
$95.51 USD -1.05 (-1.1%)
Close on Nov 2, 2026
- Day range
- $93.83 – $98.00 USDNov 2, 2026
- Volume
- 749,263 sharesNov 2, 2026
- Market cap
- $8.93B USDAt the close on Nov 2, 2026 · price × 93.45M shares outstanding
- 52-week range
- $21.15 – $110.18 USDLowest and highest trades, Nov 3, 2025 – Nov 2, 2026
- Traded on an average day
- $109.3M USDMedian day 1.04M shares · last 3 months, Aug 3, 2026 – Nov 2, 2026
Prices by listing
| Listing | Last | Change | Volume | Open | High | Low | Previous close | Price from |
|---|---|---|---|---|---|---|---|---|
| NASDAQ:SYRE · Home | $95.51 USD | -1.05 (-1.1%) | 749,263 | $97.11 | $98.00 | $93.83 | $96.56 | Close on Nov 2, 2026 |
| Frankfurt:3920 | €86.50 EUR | +4.50 (+5.5%) | — | €86.50 | €86.50 | €86.50 | €82.00 | Close on Oct 30, 2026 |
Daily closes
Last 3 months, Aug 3, 2026 – Nov 2, 2026 · NASDAQ:SYRE · USD, adjusted for splits
| Day | Close | Change | % | Open | High | Low | Volume |
|---|---|---|---|---|---|---|---|
| $95.51 | -1.05 | -1.1% | $97.11 | $98.00 | $93.83 | 749,263 | |
| $96.56 | -2.40 | -2.4% | $96.78 | $98.96 | $94.68 | 658,464 | |
| $98.96 | -0.79 | -0.8% | $99.71 | $100.42 | $97.96 | 567,627 | |
| $99.75 | +0.705 | +0.7% | $98.39 | $100.06 | $97.55 | 724,412 | |
| $99.05 | +6.135 | +6.6% | $93.00 | $99.24 | $92.95 | 944,289 | |
| $92.91 | +2.58 | +2.9% | $91.54 | $94.19 | $90.42 | 637,157 | |
| $90.33 | -2.00 | -2.2% | $90.71 | $91.90 | $88.69 | 503,000 | |
| $92.33 | -0.62 | -0.7% | $92.95 | $94.57 | $91.27 | 802,900 | |
| $92.95 | +1.55 | +1.7% | $92.78 | $95.17 | $92.32 | 1,153,100 | |
| $91.40 | +6.68 | +7.9% | $85.12 | $93.22 | $85.08 | 1,708,500 | |
| $84.72 | +4.82 | +6.0% | $82.29 | $86.05 | $80.94 | 1,272,000 | |
| $79.90 | -0.20 | -0.2% | $80.21 | $80.52 | $78.13 | 1,273,300 | |
| $80.10 | +1.47 | +1.9% | $76.87 | $80.88 | $76.87 | 1,148,000 | |
| $78.63 | -1.82 | -2.3% | $80.13 | $82.45 | $77.95 | 1,624,600 | |
| $80.45 | -5.45 | -6.3% | $85.12 | $85.32 | $80.45 | 1,441,000 | |
| $85.90 | +0.21 | +0.2% | $86.30 | $86.62 | $84.21 | 873,900 | |
| $85.69 | +5.79 | +7.2% | $79.90 | $86.22 | $78.73 | 1,116,400 | |
| $79.90 | -0.95 | -1.2% | $79.58 | $80.91 | $77.05 | 2,326,700 | |
| $80.85 | +0.74 | +0.9% | $78.91 | $82.22 | $78.00 | 2,719,300 | |
| $80.11 | -12.61 | -13.6% | $92.08 | $92.08 | $79.36 | 4,252,300 | |
| $92.72 | -0.47 | -0.5% | $93.02 | $95.01 | $89.49 | 642,800 | |
| $93.19 | +3.26 | +3.6% | $91.16 | $95.27 | $90.48 | 1,235,000 | |
| $89.93 | +0.90 | +1.0% | $89.13 | $94.06 | $87.25 | 1,662,600 | |
| $89.03 | +4.31 | +5.1% | $88.64 | $95.08 | $88.00 | 2,096,000 | |
| $84.72 | -1.07 | -1.2% | $85.09 | $86.64 | $83.26 | 1,053,200 | |
| $85.79 | +0.10 | +0.1% | $84.72 | $87.12 | $84.00 | 1,045,400 | |
| $85.69 | -1.40 | -1.6% | $88.10 | $88.10 | $85.63 | 560,100 | |
| $87.09 | -1.08 | -1.2% | $87.46 | $87.46 | $82.93 | 1,729,600 | |
| $88.17 | -3.80 | -4.1% | $91.56 | $91.56 | $86.30 | 918,800 | |
| $91.97 | -0.06 | -0.1% | $91.53 | $93.58 | $89.90 | 1,223,400 | |
| $92.03 | +1.78 | +2.0% | $91.07 | $94.06 | $89.65 | 1,448,700 | |
| $90.25 | -2.43 | -2.6% | $92.82 | $93.34 | $89.85 | 3,357,100 | |
| $92.68 | +1.51 | +1.7% | $92.86 | $95.19 | $91.14 | 1,438,900 | |
| $91.17 | +0.22 | +0.2% | $91.38 | $93.07 | $90.48 | 1,257,600 | |
| $90.95 | +0.15 | +0.2% | $90.82 | $91.07 | $88.47 | 858,500 | |
| $90.80 | +0.20 | +0.2% | $90.21 | $91.40 | $89.43 | 1,101,200 | |
| $90.60 | +1.89 | +2.1% | $90.00 | $91.41 | $87.89 | 886,100 | |
| $88.71 | +1.78 | +2.0% | $85.56 | $88.72 | $85.26 | 902,400 | |
| $86.93 | -3.86 | -4.3% | $88.07 | $89.57 | $86.85 | 1,005,800 | |
| $90.79 | +1.81 | +2.0% | $85.00 | $92.10 | $85.00 | 1,248,800 | |
| $88.98 | +1.73 | +2.0% | $86.45 | $89.18 | $84.68 | 803,800 | |
| $87.25 | +0.20 | +0.2% | $86.71 | $87.90 | $85.78 | 1,054,200 | |
| $87.05 | -1.45 | -1.6% | $88.05 | $90.18 | $84.00 | 1,361,500 | |
| $88.50 | -0.83 | -0.9% | $87.06 | $90.00 | $85.00 | 1,429,000 | |
| $89.33 | -1.03 | -1.1% | $89.15 | $90.97 | $86.40 | 1,913,200 | |
| $90.36 | -3.255 | -3.5% | $91.75 | $93.39 | $89.45 | 1,266,500 | |
| $93.62 | +0.01 | 0.0% | $93.61 | $94.95 | $91.25 | 1,165,300 | |
| $93.61 | -13.75 | -12.8% | $92.41 | $96.22 | $90.60 | 3,114,200 | |
| $107.36 | +0.71 | +0.7% | $109.02 | $110.15 | $106.94 | 923,600 | |
| $106.65 | +0.16 | +0.2% | $106.49 | $108.02 | $104.94 | 640,600 | |
| $106.49 | -1.30 | -1.2% | $108.85 | $110.00 | $105.71 | 1,014,900 | |
| $107.79 | -1.13 | -1.0% | $106.60 | $108.18 | $104.56 | 700,600 | |
| $108.92 | +1.10 | +1.0% | $110.00 | $110.18 | $104.17 | 1,166,000 | |
| $107.82 | +3.22 | +3.1% | $102.46 | $108.62 | $101.44 | 949,400 | |
| $104.60 | +0.97 | +0.9% | $102.94 | $104.96 | $102.26 | 891,500 | |
| $103.63 | +1.78 | +1.7% | $101.21 | $104.13 | $95.61 | 559,500 | |
| $101.85 | -2.24 | -2.2% | $101.00 | $103.84 | $100.90 | 525,400 | |
| $104.09 | +1.35 | +1.3% | $105.06 | $105.06 | $99.00 | 909,600 | |
| $102.74 | -2.59 | -2.5% | $105.33 | $105.44 | $99.84 | 931,700 | |
| $105.33 | +0.42 | +0.4% | $106.19 | $107.00 | $103.33 | 822,700 | |
| $104.91 | +1.49 | +1.4% | $106.01 | $106.67 | $103.64 | 526,600 | |
| $103.42 | -0.93 | -0.9% | $102.39 | $106.75 | $101.64 | 454,500 | |
| $104.35 | -0.59 | -0.6% | $104.94 | $108.14 | $100.88 | 1,037,400 | |
| $104.94 | +10.01 | +10.5% | $98.27 | $105.25 | $97.03 | 832,000 | |
| $94.93 | -3.40 | -3.5% | $97.15 | $99.58 | $92.71 | 898,400 |
- Ticker
- NASDAQ:SYRE
- Asset type
- Stock
- Sector
- Health care
- Industry
- Biotechnology
- Exchange
- NASDAQ
- Currency
- USD
What changed lately
Latest news release · Oct 18, 2026
Spyre Therapeutics Announces Clinical and Preclinical Data Presentations at United European Gastroenterology Week (UEGW) 2026
Latest deck · October 2026
Investor Presentation (October 2026)
Investor deck · 36 slides
Latest news
Spyre Therapeutics Announces Clinical and Preclinical Data Presentations at United European Gastroenterology Week (UEGW) 2026
Oct 18, 2026
Closed $84.72 (+6.0%) on Oct 19, 2026
Spyre Therapeutics Announces Pricing of $350.0 Million Public Offering of Common Stock
Oct 5, 2026
Closed $80.11 (-13.6%) on Oct 6, 2026
Spyre Therapeutics Announces Proposed Public Offering of its Common Stock
Oct 5, 2026
Closed $80.11 (-13.6%) on Oct 6, 2026
Spyre Therapeutics Announces Grants of Inducement Awards
Oct 2, 2026
Closed $92.72 (-0.5%) on Oct 5, 2026
Spyre Announces Potential Best-in-Class SPY003 (anti-IL-23) Part A Induction Results from SKYLINE Trial, Completing Proof-of-Concept for All Three Components of its IBD Combinations
Sep 8, 2026
Closed $90.79 (+2.0%) on Sep 8, 2026
Spyre Therapeutics to Participate in Upcoming September Investor Conferences
Sep 3, 2026
Closed $88.98 (+2.0%) on Sep 4, 2026
Spyre Therapeutics Announces Topline Results from the Rheumatoid Arthritis Sub-study of the SKYWAY Phase 2 Trial of SPY072
Aug 25, 2026
Closed $93.61 (-12.8%) on Aug 26, 2026
Spyre Therapeutics Announces Launch of SPY772 Program and Initiation of Phase 2 SKYLIGHT Trial in Hidradenitis Suppurativa
Aug 10, 2026
Closed $105.33 (+0.4%) on Aug 10, 2026
Spyre Therapeutics Reports Second Quarter 2026 Financial Results and Provides Corporate Update
Aug 4, 2026
Closed $104.35 (-0.6%) on Aug 5, 2026
Financings
Public offering of common stock
Oct 6, 2026
Update: about US$350M · US$85 a share · Jefferies +4
Dealers: Jefferies (co-lead), TD Cowen (co-lead), Leerink Partners (co-lead), Stifel (co-lead), LifeSci Capital
Use of proceeds: Advance Gastroenterology, Rheumatology and Dermatology programs, including Phase 3 readiness, and SPY072 for hidradenitis suppurativa
Decks
Investor Presentation (October 2026)
Investor deck · 36 slides · October 2026
Technical Presentation (April 2026)
Technical · 31 slides · Apr 13, 2026
Investor Presentation (January 2026)
Investor deck · 38 slides · Jan 12, 2026
Technical Presentation (June 2025)
Technical · 36 slides · Jun 17, 2025
Spyre Therapeutics, Inc. on 6ix
- Sector
- Health care
- Industry
- Biotechnology
- News releases
- 24 in the last 12 months · 145 in all · newest Oct 18, 2026 · oldest 2019
- Decks
- 32 decks · latest October 2026
Where Spyre Therapeutics, Inc. is listed
| Listing | Exchange | Country | Currency |
|---|---|---|---|
| NASDAQ:SYRE · Home listing · This page | NASDAQ | United States | USD |
| LS Exchange:A3D4LY | LS Exchange | Germany | EUR |
| BOATS:SYRE | BOATS | United States | USD |
| Lang & Schwarz:A3D4LY | Lang & Schwarz | Germany | EUR |
| Dusseldorf:3920 | Dusseldorf | Germany | EUR |
| Tradegate:3920 | Tradegate | Germany | EUR |
| Stuttgart:3920 | Stuttgart | Germany | EUR |
| Frankfurt:3920 | Frankfurt | Germany | EUR |
| gettex:3920 | gettex | Germany | EUR |
| Munich:3920 | Munich | Germany | EUR |
| Xetra:3920 | Xetra | Germany | EUR |
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