Masimo Corporation · NASDAQ:MASI

Masimo — Investor Day (May 2019)

118 slides from Masimo's investor day presentation, May 16, 2019

  1. Slide 1: Investor Day

    Investor Day Improving Patient Outcomes May 16, 2019 Reducing the Cost of Care®

  2. Slide 2: Agenda

    Agenda Registration 8:00am - 8:30am Breakfast 8:30am - 9:40am Managem ent Presentations 9:40am - 9:50am Break 9:50am - 11:00am Managem ent Presentations 11:00am - 1:30pm Lunch and Technology Dem onstrations 1:30pm - 2:00pm Executive Q&A and Closing Com m ents

  3. Slide 3: Forward-Looking Statements

    FORWARD-LOOKING STATEMENTS These presentations contain forward-looking statements within the meaning of federal securities laws, including, among others, statements about our expectations, plans, strategies or prospects. We generally use the words “may,” “will,” “expect,” “believe,” “anticipate,” “p

  4. Slide 4: Non-GAAP Financial Measures

    NON-GAAP FINANCIAL MEASURES The non-GAAP financial measures contained herein are a supplement to the corresponding financial measures prepared in accordance with U.S. generally accepted accounting principles (GAAP). The non-GAAP financial measures presented exclude certain items that are more fully

  5. Slide 5: Joe Kiani

    Joe Kiani Chairman and Chief Executive Officer

  6. Slide 6: Mission Statement

    MISSION STATEMENT Improving Patient Outcomes and Reducing the Cost of Care® GUIDING PRINCIPLES § Remain faithful to your promises and responsibilities § Thrive on fascination and accomplishment and not on greed and power § Strive to make each year better than the year before, both personally and for

  7. Slide 7: Innovation Timeline

    Innovation Timeline T h e u s e o f th e tr a d e m a r k P A T IE N T S A F E T Y N E T is u n d e r lic e n s e fr o m U n iv e r s ity H e a lth S y s te m C o n s o r tiu m . O R i is p e n d in g 5 1 0 k c le a r a n c e . N o t a v a ila b le in th e U .S . o r C a n a d a . H a lo In d e x h

  8. Slide 8: Strong Track Record of Growth Since IPO

    Strong Track Record of Growth Since IPO Product Revenue ($ in Millions) $918 $830 $738 $674 $599 $557 $517 $465 $406 $356 $300 $260 $200 13.5% CAGR 20 07 20 08 20 09 20 10 20 11 20 12 20 13 20 14 20 15 20 16 20 17 20 18 20 19 E

  9. Slide 9: Executing on Our Long-Term Plan

    Executing on Our Long-Term Plan Product Revenue ($ in Millions) L o n g -T e rm P la n (2 0 1 7 In ve sto r D a y) C u rre n t T ra je cto ry 1 $1, 40 0 $1, 20 0 $1, 00 0 $80 0 $60 0 $40 0 20 17 20 18 20 19 E 20 20 E 20 21 E 20 22 E 20 23 E 20 24 E 1 Current trajectory based on our 2019 guidance of

  10. Slide 10: Revenue Performance by Technology Platform

    Revenue Performance by Technology Platform Masimo Revenue Growth % (FY 2018 vs. FY 2017) 3 0% 2 5% 2 0% 1 5% 1 0% 5% 0% SET® ra in bo w® No mo Li ne ®, Sed L n i e®, a nd O3® A c tu a l R e ve n u e G ro w th (F Y 2 0 1 8 vs . F Y 2 0 1 7 ) L T P G ro w th T a rg e ts b y P la tfo rm

  11. Slide 11: Delivering Significant Shareholder Value

    Delivering Significant Shareholder Value Total Shareholder Return (12/31/2017 – 5/10/2019) 165 M a s im o (M A S I) 65% U S M e d ic a l D e v ic e s E T F (IH I) 155 N A S D A Q C o m p o site 145 S&P 500 135 28% 125 115 15% 105 8% 95 85 12 /2 9/ 17 03 /2 9/ 18 06 /2 9/ 18 09 /2 9/ 18 12 /2 9/ 18 0

  12. Slide 12: Long-Term Plan

    Long-Term Plan GROWTH AND INDUSTRY-LEADING DISCIPLINED CAPITAL PROFITABILITY INNOVATIONS DEPLOYMENT § Revenue growth of 8 – 10% § Innovation never stops at § Reinvest to drive innovation Masimo! § Operating margins of 30% § Strategic acquisitions § Hospital automation § EPS growth of 12 – 15% § Sele

  13. Slide 13: lt qa

    lt qa

  14. Slide 14: Strategic Initiatives: Hospital Automation

    Strategic Initiatives: Hospital Automation PROBLEM STATEMENT: Care delivery can be inefficient, with a high degree of variability in quality and cost. § Cognitive overload and errors of omission are hurting patients and leading to burn out § Disparate data sources § Complex workflows: manual documen

  15. Slide 15: Opioid Safety in Hospitals

    Opioid Safety in Hospitals § Conventional pulse oximetry failed in the general ward due to high false alarm rates § Masimo SET ® enabled monitoring in the general ward § Patient SafetyNet™ is deployed in over 400 hospitals 1 Taenzer A.H.et al. APSF Newsletter 2012. Available at:http://www.apsf.org/n

  16. Slide 16: Opioid Safety in the Home

    Opioid Safety in the Home § We believe we can have the same impact wherever opioids are used, including the home § Opioid SafetyNet™ was selected by the FDA for their Opioid Epidemic Challenge § Granted designation as a breakthrough device

  17. Slide 17: Current Portfolio Market Opportunity

    Current Portfolio Market Opportunity1 Total Addressable Market Opportunity $4.5B Current Portfolio Markets 1 ü P u lse O xim e try ü P u lse C O -O xim e try $3.0B ü C a p n o g ra p h y ü B ra in F u n ctio n M o n ito rin g ü R e g io n a l O xim e try ü T e le h e a lth , C o n s u m e r, a n d G

  18. Slide 18: Potential to Expand Our Long-Term Market Opportunity

    Potential to Expand Our Long-Term Market Opportunity Total Addressable Market Opportunity Innovation Pipeline Opportunities Pipeline Opportunity $1.0B $5B+ Pipeline Opportunity $0.5B Pipeline Opportunity $0.2B Pipeline Opportunity $1.0B Pipeline Opportunity $1.0B+ $4B+ $15B+ Pipeline Opportunity $1.

  19. Slide 19: Key Takeaways

    Key Takeaways § Our relentless focus on patient safety has not only benefited patients, clinicians, and hospitals, but also Masimo shareholders § Dedicated and talented team has consistently delivered on our commitments § Long-term revenue growth of 8 – 10% with upside potential § Hospital Automatio

  20. Slide 20: Bilal Muhsin

    Bilal Muhsin Chief Operating Officer

  21. Slide 21: Global Reach

    Global Reach 150+ countries 100 Million+ patients Large installed base of Partnerships with impacted each year technology boards and OEMs monitors

  22. Slide 22: Technology Boards and Monitors

    Technology Boards and Monitors Growing Installed Base of Masimo Technology Boards and Monitors ~1.7 Million + = sh ip p e d o ve r la s t 1 0 ye a rs Technology Boards Monitors Over 200 multi-parameter monitors and devices from Shipped ~1.7 million technology boards and 70 leading brands have integr

  23. Slide 23: Pulse Oximetry Market: $1.7 Billion Market

    Pulse Oximetry Market: $1.7 Billion Market U.S. Hospital Continuous Monitoring Penetration 5 00 § SpO2 is Standard of Care 4 50 § Critical Care (OR, NICU, and ICU) 4 00 § Emergency Medical Settings Thousands of beds 3 50 3 00 2 50 § Expansion Opportunity 2 00 § General floor ~10% penetrated 1 50 § L

  24. Slide 24: Masimo SET

    Masimo SET® Measure-through Motion and Low Perfusion™* Pulse Oximetry * M a s im o S E T ® M e a s u r e - th r o u g h M o tio n te c h n o lo g y in c lu d e s S p O 2 a n d P R . C o n tin u o u s m o n ito r in g w ith R R p h a s o b ta in e d C E M a r k in g . N o t a v a ila b le in th e U .

  25. Slide 25: Masimo SET

    Masimo SET® § Prior to Masimo Signal Extraction Technology® (SET®), pulse oximetry was unreliable when it was needed most, during patient motion and low perfusion. § Masimo SET® works by recognizing that both arterial and venous blood can move. § Using parallel signal processing engines — DST, FST,

  26. Slide 26: Masimo SET

    Masimo SET® Over 100 independent and objective studies have shown that Masimo SET® outperforms other pulse oximetry technologies during motion and low perfusion conditions, providing clinicians with increased sensitivity and specificity to help them make critical patient care decisions.* These indep

  27. Slide 27: Masimo SET

    Masimo SET® Masimo SET® had 3% missed true alarms and 5% false alarms versus 43% and 28%, respectively, using competitor technology. 1 S h a h N e t a l. J C lin A n e s th . 2 0 1 2 A u g ;2 4 ( 5 ) :3 8 5 - 9 1 . R e s u lts s h o w n a r e c a lc u la te d b y c o m b in in g s e n s itiv ity a n

  28. Slide 28: Masimo SET

    Masimo SET® In the NICU Rates of Retinopathy of Prematurity in Very Low Birth Weight Infants § Post-Masimo SET® and new protocol, the incidence of retinopathy of prematurity (ROP), stages 3 to 4, decreased from 12.5% to 2.5% in very low birth weight infants over a five-year period. In cid e n ce o f

  29. Slide 29: Masimo SET

    Masimo SET® In the NICU § Researchers found that Masimo SET® , in combination with changes in clinical policy, led to a reduction in severe retinopathy of prematurity (ROP). 1 C a s tillo A e t a l. A c ta P a e d ia tr . 2 0 1 1 F e b ;1 0 0 ( 2 ) :1 8 8 - 9 2 .

  30. Slide 30: Masimo SET

    Masimo SET® Newborn Screening § In a study of 122,738 infants, critical congenital heart disease (CCHD) screening sensitivity increased from 77% to 93% with the combined use of Masimo SET® and clinical assessment. Z h a o e t a l. L a n c e t. 2 0 1 4 A u g 3 0 ;3 8 4 ( 9 9 4 5 ) :7 4 7 - 5 4 .

  31. Slide 31: Improved Outcomes with Patient SafetyNet and SET

    Improved Outcomes with Patient SafetyNet™ and SET® Researchers found improved outcomes following installation of continuous postoperative monitoring. 1 T a e n z e r A H e t a l. A n e s th e s ia P a tie n t S a fe ty F o u n d a tio n N e w s le tte r . S p r in g - S u m m e r 2 0 1 2 . 2 M c G r

  32. Slide 32: SpO2 Accuracy Improvement

    SpO2 Accuracy Improvement We Just Raised the SpO2 ARMS* Accuracy for RD SET™ Sensors Standard, Again Past outcomes were achieved with Previous Im proved 3% accuracy during motion. Now Motion 3% 1.5% SpO2 accuracy has improved, providing clinicians with greater confidence when monitoring No Motion 2%

  33. Slide 33: Radius PPG in the Hospital

    Radius PPG™ in the Hospital § Tetherless Masimo SET® solution that improves patient comfort and mobility § Reusable + disposable component § 4-day battery life § Compatible with existing Masimo SET ® installed base

  34. Slide 34: PVi - During Surgery

    PVi® - During Surgery Over 100 studies have evaluated the utility of Pleth Variability Index (PVi). Study Conclusion Comparing Masimo PVi to Invasive § PVi . . . can predict fluid responsiveness Measurement Technologies non-invasively in mechanically ventilated patients during general anesthesia. Th

  35. Slide 35: Dynamic PVi

    Dynamic PVi Compared to PVi, a new dynamic PVi mode is designed to provide: § A reduction in variability under certain conditions § Fewer post-dropout spikes

  36. Slide 36: RRp

    RRp® With Respiration Rate from the Pleth (RRp), Masimo provides another method of measuring respiration rate. Measurement Patient Population ARMS* Range 3 RPM Adult/Pediatric 4-70 RPM +1 RPM mean error Changes in the Plethysmographic Waveform During Breathing * A RMS a c c u r a c y i s a s t a t i

  37. Slide 37: Masimo SET

    Masimo SET® Pulse Oximetry C o n tin u o u s m o n ito r in g w ith R R p h a s o b ta in e d C E M a r k in g . N o t a v a ila b le in th e U .S .

  38. Slide 38: Masimo rainbow

    Masimo rainbow® Pulse CO-Oximetry C o n tin u o u s m o n ito r in g w ith R R p h a s o b ta in e d C E M a r k in g . O R i is p e n d in g 5 1 0 k c le a r a n c e . N o t a v a ila b le in th e U .S .

  39. Slide 39: SpHb

    SpHb® Continuous hemoglobin monitoring (SpHb) provides real-time visibility to changes in hemoglobin between invasive blood samples. S p H b m o n ito r in g is n o t in te n d e d to r e p la c e la b o r a to r y b lo o d te s tin g . B lo o d s a m p le s s h o u ld b e a n a ly z e d b y la b o

  40. Slide 40: SpHb Utility

    SpHb Utility • In a randomized trial of 327 patients undergoing elective orthopedic surgery conducted at Massachusetts General Hospital (MGH), researchers found that the use of continuous, noninvasive hemoglobin monitoring reduced the rate of transfusions when compared to standard care without conti

  41. Slide 41: SpHb Utility

    SpHb Utility In a prospective cohort study of 106 neurosurgical patients, researchers found that adding SpHb monitoring to standard-of-care blood management resulted in decreased blood utilization in high-blood-loss neurosurgery, while also facilitating earlier transfusions.1* * Study Protocol: The

  42. Slide 42: SpHb and PVi: Impact on Morbidity and Mortality

    SpHb and PVi: Impact on Morbidity and Mortality Clinical Study Investigates the Impact of SpHb and PVi on Anesthesia-related Mortality1 SpHb and PVi Improved Outcomes in Reduction in Mortality Between Non-SpHb/PVi Surgical Patients Group and SpHb/PVi Group § 18,000+ patients § All patients monitored

  43. Slide 43: SpHb Plot Comparison with Rev E vs Rev O

    SpHb Plot Comparison with Rev E vs Rev O Masimo engineering data.

  44. Slide 44: Oxygen Reserve Index (ORi)

    Oxygen Reserve Index (ORi™) § In Europe, ORi has obtained CE Marking as the first noninvasive and continuous parameter to provide insight into a patient’s oxygen reserve. § ORi is pending 510(k) clearance and is not available in the U.S.

  45. Slide 45: SET and rainbow: Sensor Options

    SET® and rainbow® : Sensor Options The Power of the rainbow ® Platform 2 LED 4 LED 8 LED 10 LED O R i, R P V i a n d c o n tin u o u s R R p m o n ito r in g h a v e o b ta in e d C E M a r k in g . N o t a v a ila b le in th e U .S .

  46. Slide 46: RRa Acoustic Respiratory Monitoring

    RRa® Acoustic Respiratory Monitoring In a study of RRa vs capnography, researchers concluded that “The data from this study demonstrate that acoustic monitoring provides a very reliable noninvasive, continuous method for estimating ventilatory rate in postsurgical patients at risk for ventilatory co

  47. Slide 47: RRa

    RRa Acoustic Respiration Rate (RRa) has been shown to be: § accurate1 ,2 § reliable1 § easy-to-use1 § easy-to-tolerate1 ,3 …enhancing patient compliance with respiration monitoring. 1 M a c k n e t M R e t a l. A n e s th e s io lo g y . 2 0 0 7 ;1 0 7 :A 8 4 ( a b s tr a c t) . 2 G o u d r a B G e

  48. Slide 48: Estimated Potential Savings with Masimo SET and rainbow Parameters

    Estimated Potential Savings with Masimo SET ® and rainbow ® Parameters Estimates based on a 250-bed hospital model § SET ® + rainbow: >$3M in annual cost savings

  49. Slide 49: Advanced Parameter Monitoring

    Advanced Parameter Monitoring SedLine O3 NomoLine Brain Function – Depth of Sedation Regional Oximetry Capnography and Gas Monitoring

  50. Slide 50: Next Generation SedLine Brain Function Monitoring

    Next Generation SedLine® Brain Function Monitoring Next Generation SedLine Brain Function Monitoring helps clinicians monitor the state of the brain under anesthesia with bilateral data acquisition and processing of electroencephalogram (EEG) signals. EEG PSi DSA Burst Suppression

  51. Slide 51: Next Generation SedLine Brain Function Monitoring

    Next Generation SedLine Brain Function Monitoring Improved PSi Performance During Low Power EEG Next Generation SedLine uses adaptive signal processing with band-independent features to offer improved PSi performance in cases of low power EEG.

  52. Slide 52: Next Generation SedLine Brain Function Monitoring

    Next Generation SedLine Brain Function Monitoring § Reduces Electromyography (EMG) § Next Generation SedLine extracts a clearer EEG signal for computing PSi

  53. Slide 53: O3 Regional Oximetry

    O3® Regional Oximetry O3 may help clinicians monitor cerebral oxygenation in situations in which peripheral pulse oximetry alone may not be fully indicative of the oxygen in the brain.

  54. Slide 54: A More Complete Picture of the Brain

    A More Complete Picture of the Brain Next Generation SedLine can be used simultaneously with O3 Regional Oximetry on the Root platform for a more complete picture of the brain. The RD SedLine™ sensor is designed for seamless, simultaneous application with O3 sensors.

  55. Slide 55: Capnography and Airway Gas Monitoring Solutions

    Capnography and Airway Gas Monitoring Solutions Masimo offers a variety of capnography and gas solutions, including external modules and both mainstream and sidestream options. EMMA™ EtCO2, RR

  56. Slide 56: NomoLine Sampling Lines

    NomoLine® Sampling Lines No-moisture sampling lines for intubated and non-intubated patients in low- and high- humidity applications, supporting all patient populations.

  57. Slide 57: NomoLine Sampling Lines

    NomoLine® Sampling Lines How it Works Gas and condensed moisture from the patient enters through the gas sample tube. Condensed moisture and aspirated water are separated and collected using a hydrophilic absorbent, then diffused through the polymer cover and evaporated into the surrounding air.

  58. Slide 58: Portable Devices

    Portable Devices § Rad-67™ Handheld Pulse CO-Oximeter® (SpHb®) § Rad-57® Handheld Pulse CO-Oximeter (SpCO®) § EMMA™ Capnograph § MighytSat® Rx Pulse Oximeter

  59. Slide 59: Large and Growing Markets

    Large and Growing Markets Growth Estimates: 2019 – 2024 CAGR SET® rainbow® NomoLine® SedLine® Brain O3® Regional Pulse Oximetry Pulse CO-Oximetry Capnography Function Monitoring Oximetry Market ~$1.7B ~$1B ~$550M ~$125M ~$125M (TAM) Clinical #1 #1 #1 #1 #1 Leadership Market #1 #1 #3 #2 #3 Leadership

  60. Slide 60: Agenda

    Agenda Registration 8:00am - 8:30am Breakfast 8:30am - 9:40am Managem ent Presentations 9:40am - 9:50am Break 9:50am - 11:00am Managem ent Presentations 11:00am - 1:30pm Lunch and Technology Dem onstrations 1:30pm - 2:00pm Executive Q&A and Closing Com m ents

  61. Slide 61: Hospital Automation

    Hospital Automation

  62. Slide 62: Market Needs and Challenges

    Market Needs and Challenges § Many devices with many interfaces Cognitive overload and § Difficult to interpret multiple points errors of omission of data at once § Low nurse-to-patient ratio Data accessibility § Patients out of visual and auditory range § Manual charting and Complex workflows trans

  63. Slide 63: Competitive Solutions

    Competitive Solutions Point-of-care Device Middleware Destination Cockpit Cockpit Server Display Pump Gateway Infusion Pump Alarm Manager Monitor Central Gateway Station Physiological Monitor Alarm Reporter Ventilator Gateway Mobile Device Anesthesia/ Ventilator Mobile Data Server Integration Integr

  64. Slide 64: Masimo Solution

    Masimo Solution Point-of-care Device Middleware Destination Cockpit UniViewTM Display Infusion Pump Central Patient Station SafetyNetTM Physiological Monitor Iris® Platform Root® Mobile Device ReplicaTM Ventilator EMR Iris®

  65. Slide 65: Iris Platform

    Iris® Platform Parameter Data Waveform Data Alarms and 2-way Audio Events and Video High-fidelity, Low-latency Bus Architecture That Enables Unique Solutions Across All Care Areas

  66. Slide 66: Root

    Root® Expandable, Versatile, and Customizable Patient Monitoring and Connectivity Hub SedLine® NomoLine® Vital Signs Brain Function Capnography Check Monitoring & Airway Gas Automating Data Collection Radical-7® O3® Radius-7® SET® and Regional Ambulatory rainbow® Oximetry Monitoring

  67. Slide 67: Device Integration

    Device Integration Third-Party Devices Root Iris Platform EMR ACE™ (Adaptive Connectivity Engine™) § Easily integrate third-party device data § Seamlessly map parameters to a variety of EMRs

  68. Slide 68: UniView – Cockpit Display

    UniView™ – Cockpit Display

  69. Slide 69: Patient SafetyNet – Supplemental Remote Central Monitoring

    Patient SafetyNet™ – Supplemental Remote Central Monitoring

  70. Slide 70: Replica – Mobile Data and Alarm Notifications

    Replica™ – Mobile Data and Alarm Notifications

  71. Slide 71: Root – with Automated Vital Signs Workflow

    Root – with Automated Vital Signs Workflow Continuous Monitor Vital Signs Check

  72. Slide 72: Halo ION – Comprehensive, Personalized, Continuous Patient Score

    Halo ION™ – Comprehensive, Personalized, Continuous Patient Score

  73. Slide 73: Iris Device Management System

    Iris® Device Management System™

  74. Slide 74: Automation Across the Continuum of Care

    Automation Across the Continuum of Care OR ICU Med-S. General IT/Biomed

  75. Slide 75: Masimo Patient SafetyNet

    Masimo Patient SafetyNet™ • Researchers found improved outcomes following installation of continuous postoperative monitoring using Masimo SET® 2 1 2 1 1 T a e n z e r A H e t a l. A n e s th e s ia P a tie n t S a fe ty F o u n d a tio n N e w s le tte r . S p r in g - S u m m e r 2 0 1 2 . 2 M c G

  76. Slide 76: Impactful Beginnings of Hospital Automation

    Impactful Beginnings of Hospital Automation Following the implementation of an enhanced monitoring system with Root, Radius-7 and Patient SafetyNet, researchers found increased continuous patient monitoring hours and reduced vital signs documentation time. The study concluded: § 28% reduced average

  77. Slide 77: Market Opportunity

    Market Opportunity § Global TAM of ~$1.5B OUS § Capital and service revenue US § 18 – 24 month contracting cycle § Robust pipeline of opportunities US Market Total Penetration Potential Range of ASPs Beds Beds per bed Critical Care 125,000 100% 125,000 General Floor 450,000 50% 225,000 Total 575,000

  78. Slide 78: Market Needs and Challenges

    Market Needs and Challenges • Many devices with many interfaces Cognitive overload and • UniView: • Difficult patientmultiple to interpret cockpit points errors of omission • Halo ION: continuous scoring of data at once • Low nurse to patient ratio • Patient • Patients outSafetyNet of visual and Dat

  79. Slide 79: Homecare

    ) — © ) 0) = fe) LL

  80. Slide 80: Masimo Homecare Solutions

    Masimo Homecare Solutions [ DOCTELLA® }

  81. Slide 81: CareProgram

    CareProgram™ Clinician-designed CareProgram Clinician Dashboard Consent Notifications CareProgram Detailed Patient View

  82. Slide 82: Rad-97 for Telemedicine and Homecare

    Rad-97 for Telemedicine and Homecare

  83. Slide 83: Hospital Automation

    Hospital Automation

  84. Slide 84: Opioid Safety

    Opioid Safety

  85. Slide 85: Opioid Definition

    Opioid Definition Prescription pain relievers: oxycodone (OxyContin®), hydrocodone (Vicodin®), morphine, codeine, fentanyl Illicit drug use: heroin and synthetic opioids such as fentanyl Opioid receptors work on nerve cells to produce pleasurable effects and relieve pain Primary use of prescription

  86. Slide 86: Opioid Use Frequency

    Opioid Use Frequency • 191 million prescriptions per year1 • 92 million adults use a prescription opioid each year2 • 114,000 U.S. emergency department visits per year due to suspected opioid overdose3 • Total economic burden of prescription opioids per year in the U.S. is $78.5 billion4 1C e n t e

  87. Slide 87: Physiological Effects of Opioids

    Physiological Effects of Opioids § Opioids are potent respiratory depressants § During opioid overdose, oxygen deprivation leads to brain injury and death § Cardiac arrest is a late complication of opioid overdose and secondary to Add Graphic respiratory arrest and hypoventilation § People can have

  88. Slide 88: Common Approach to Opioid Epidemic

    Common Approach to Opioid Epidemic Public Health Efforts to Address Crisis § Reduce availability § Fewer prescriptions § Reduce prescribed doses § Treatment to addiction § Reversal drug availability

  89. Slide 89: The United States Has an Opioid Safety Crisis

    The United States Has an Opioid Safety Crisis 47,600 Opioid-related Deaths in 2017 National Drug Overdose Deaths Involving Any Opioid1 National Drug Overdose Deaths Involving Prescription Opioids1 Number Among All Ages, 1999-2017 Number Among All Ages, 1999-2017 50, 000 4 7 ,6 0 0 18, 000 1 7 ,0 2 9

  90. Slide 90: Masimo SET Pulse Oximetry Solution

    Masimo SET® Pulse Oximetry Solution § Masimo SET® can provide effective pulse oximetry monitoring in the home just as it already does in the hospital § Patients already use Masimo hospital devices at home § Now we are designing a product specifically intended for monitoring patients on opioids

  91. Slide 91: Opioid SafetyNet

    Opioid SafetyNet™ § Addresses the danger of opioid- induced respiratory depression with a convenient, intuitive combination of patient sensor, hub, and smartphone app

  92. Slide 92: Opioid Market Opportunity

    Opioid Market Opportunity § 191 million opioid prescriptions in 2017 § Assume 30% reduction in prescriptions due to efforts to reduce opioid use § 134 million prescription opportunity § Initial focus on 1/3 of the population (chronic pain management and postoperative patients) § 45 million prescript

  93. Slide 93: Utah, First to Act

    Utah, First to Act May 2018: Utah State Legislature introduces the “Parker Bill” Utah Resolution Key Points: § Recognizes the effects of sudden death from opioid- induced postoperative respiratory depression § Urges the Department of Health, hospitals, practitioners, and academics to further study t

  94. Slide 94: Measured Approach to Launch

    Measured Approach to Launch § Partnering closely with FDA § Starting with cash pay patients § Pursuing reimbursement model

  95. Slide 95: Opioid Safety: Key Takeaways

    Opioid Safety: Key Takeaways § Potentially thousands of lives saved a year § Masimo SET® technology is the enabler § Measured market launch to ensure commercialization success

  96. Slide 96: Stacey Orsat

    Stacey Orsat President EMEA

  97. Slide 97: Global Health: Scale-up Access to Safe Surgery

    Global Health: Scale-up Access to Safe Surgery 5 Billion without access to safe surgery1 § 33% of all deaths/year = 17M deaths § 77 million DALYs (Disability Adjusted Life Years) § In low income countries there is a higher proportion of amenable deaths among health system users than non-users2 § Dat

  98. Slide 98: Global Health: Scale-up Detection of Pneumonia

    Global Health: Scale-up Detection of Pneumonia 200 Million pneumonia cases occur each year around the world 1 § 2.6M deaths per year § Children under the age of 5 and the elderly have highest risk § Not enough done globally to identify and treat pneumonia In 2013 The Bill & Melinda Gates Foundation

  99. Slide 99: Global Health: Scale-up Screening for Anemia

    Global Health: Scale-up Screening for Anemia 1/3 of the world’s population is anemic1, contributing to: § 9% of disabilities worldwide § 42% increase in mortality during surgery SpHb screening is beginning, with the largest global Hb screening projects conducted by largest international NGO and gove

  100. Slide 100: Corporate Responsibility and Sustainability

    Corporate Responsibility and Sustainability Investing in improving our footprint in our world and our community Investing in our Planet and our Team § RD sensors vs. traditional cabled-based sensors led to 84% waste reduction § RD sensors has saved approximately 1.5M lbs of CO2 since 2016 § 1M+ lbs

  101. Slide 101: Investing in Our Community

    Investing in Our Community Partnering on broad patient safety initiatives Partnering in housing homeless people in OC

  102. Slide 102: Micah Young

    Micah Young Executive Vice President and Chief Financial Officer

  103. Slide 103: Long-Term Financial Goals and Objectives

    Long-Term Financial Goals and Objectives MARKET LEADING Revenue growth of 8 – 10% REVENUE GROWTH OPERATING MARGIN Non-GAAP Operating Margins of 30% EXPANSION SIGNIFICANT EPS Non-GAAP EPS growth of 12 – 15% GROWTH STRONG CASH FLOW Adjusted Free cash flow of $300M+ GENERATION DISCIPLINED CAPITAL Strat

  104. Slide 104: Executing on Our Long-Term Plan

    Executing on Our Long-Term Plan N o n -G A A P 1 N o n -G A A P 1 Product Revenue Operating Margin EPS $918M 24.0% $3.12 $830M 22.0% $2.65 $738M 18.6% $1.73 +11.5% CAGR +540 bps +34% CAGR 2 01 7 2 01 8 2 01 9 E 2 01 7 2 01 8 2 01 9 E 2 01 7 2 01 8 2 01 9 E 1 N o n - G A A P m e a s u r e s s h o w n

  105. Slide 105: Long-Term Revenue Growth of 8 – 10%

    Long-Term Revenue Growth of 8 – 10% Multiple opportunities for upside… Potential to Expand Our Long-term Market Opportunity Total Addressable Market Opportunity Innovation Pipeline Opportunities Pipeline Opportunity $1.0B $5B+ Pipeline Opportunity $0.5B Pipeline Opportunity $0.2B Pipeline Opportunit

  106. Slide 106: Non-GAAP Operating Margin Improvement

    Non-GAAP Operating Margin1 Improvement Targeting Long-Term Operating Margins of ~30% ~30% ~600 Basis Points of Operating Margin Im provem ent § Gross margin improvement of ~320 bps 24.0% 22.0% § Operating expense improvement of ~280 bps § SG&A expenses will be the primary driver 18.6% § Maintain our

  107. Slide 107: Non-GAAP Gross Margin Improvement

    Non-GAAP Gross Margin1 Improvement Targeting Long-Term Gross Margins of ~70% ~70% ~320 Basis Points of Gross Margin Im provem ent 66.8% § Manufacturing scale 66.0% § Design for manufacturability (DFM) 64.2% § Procurement initiatives § Leveraging our installed base +320 bps 2 01 7 2 01 8 2 01 9 E L T

  108. Slide 108: Non-GAAP Operating Expense Improvement

    Non-GAAP Operating Expense1 Improvement Targeting Long-Term Operating Expenses of ~40% 45.7% ~280 Basis Points of 44.0% Operating Expense Im provem ent 42.8% § International scale ~40% § U.S. commercial productivity § G&A leverage and efficiency -280 bps 2 01 7 2 01 8 2 01 9 E L TP Targ e t 1 N o n

  109. Slide 109: Strong Cash Flow Generation

    Strong Cash Flow Generation Adjusted Free Cash Flow1 TARGETING LONG-TERM $ in Millions FREE CASH FLOW OF $300M+ $300M+ § Execute on our long-term revenue and profitability goals to increase cash flow $222M § Maintain the improvements we made to working capital Royalties in FY 2018 Working Capital Im

  110. Slide 110: Disciplined Capital Deployment

    Disciplined Capital Deployment STRATEGIC SHARE REINVESTMENT ACQUISITIONS REPURCHASES Reinvest in the business to drive Execute acquisitions that align Selective share repurchases further innovation well with our long-term strategy § Maintain our R&D investment § Leverage our core competencies § Disc

  111. Slide 111: Key Takeaways

    Key Takeaways § Executing on our long-term plan § Long-term revenue growth target of 8 – 10% has multiple opportunities for upside § Hospital Automation § Opioid Safety § Innovation Pipeline

  112. Slide 112: Investor Day Appendix

    Investor Day Appendix May 16, 2019

  113. Slide 113: Constant Currency Product Revenue

    Constant Currency Product Revenue 1,2 RECONCILIATION OF GAAP PRODUCT REVENUE GROWTH TO CONSTANT CURRENCY PRODUCT REVENUE GROWTH (3) (in thousands, except percentages) YTD 2017 YTD 2018 2019 Guidance GAAP product revenue $ 738,242 $ 829,874 $ 918,000 Constant currency F/X adjustments N/A N/A 6,500 Co

  114. Slide 114: Non-GAAP Gross Margin %

    Non-GAAP Gross Margin % 1,2 RECONCILIATION OF GAAP GROSS PROFIT/MARGIN TO NON-GAAP GROSS PROFIT/MARGIN: (3) (in thousands, except percentages) YTD 2017 YTD 2018 2019 Guidance GAAP gross profit/margin $ 522,032 $ 574,892 $ 613,814 Non-GAAP adjustments: Royalty and other revenue, net of related costs

  115. Slide 115: Non-GAAP Operating Expense %

    Non-GAAP Operating Expense % 1,2 RECONCILIATION OF GAAP OPERATING EXPENSES TO NON-GAAP OPERATING EXPENSES: (3) (in thousands, except percentages) YTD 2017 YTD 2018 2019 Guidance GAAP selling, general and administrative operating expenses $ 273,011 $ 285,417 Non-GAAP adjustments: Acquisition-related

  116. Slide 116: Non-GAAP Operating Margin %

    Non-GAAP Operating Margin % 1,2 RECONCILIATION OF GAAP OPERATING INCOME/MARGIN TO NON-GAAP OPERATING INCOME/MARGIN: (3) (in thousands, except percentages) YTD 2017 YTD 2018 2019 Guidance GAAP operating income/margin $ 183,787 $ 208,044 $ 219,938 Non-GAAP adjustments: Royalty and other revenue, net o

  117. Slide 117: Non-GAAP Net Income and Diluted EPS

    Non-GAAP Net Income and Diluted EPS 1,2 RECONCILIATION OF GAAP NET INCOME TO NON-GAAP NET INCOME: (3) (in thousands, except per share amounts) YTD 2017 YTD 2018 2019 Guidance GAAP net income $ 124,789 $ 193,543 $ 186,925 Weighted Average Shares Outstanding - diluted 55,874 56,039 57,599 GAAP Net Inc

  118. Slide 118: Adjusted Free Cash Flow

    Adjusted Free Cash Flow 1,2 RECONCILIATION OF FREE CASH FLOW TO ADJUSTED FREE CASH FLOW (in thousands) YTD 2017 YTD 2018 Net cash provided by operating activities Net cash provided by operating activities $ 56,062 $ 239,527 Purchases of property and equipment, net (43,684) (17,126) Free cash flow 12

Masimo — Investor Day (May 2019) on 6ix