Algorae Pharmaceuticals Limited · ASX:1AI

Algorae Pharmaceuticals — Investor Presentation (October 2026)

21 slides from Algorae Pharmaceuticals's investor presentation, Oct 30, 2026

  1. Slide 1: Accessible care, Advanced science, A healthier future

    ASX:1AI · Non-deal Presentation · OCTOBER 2026 Accessible care Advanced science A healthier future

  2. Slide 2: Important notice and disclaimer

    Important notice and disclaimer This presentation has been prepared by Algorae Pharmaceuticals Limited (“Algorae” No Liability The information contained in this presentation has been prepared in Forward-looking statements, opinions and estimates provided in this presentation or the “Company”) based

  3. Slide 3: Our model: Two engines, independent validation, commercial execution underway

    Our model Two engines. Independent validation. Commercial execution underway Near-term revenue Longer-dated optionality AlgoraeRx 6+ Manufacturing partners AlgoraeOS Sourcing, licensing and supplying generic and specialty medicines across AI drug discovery platform identifying synergistic drug combi

  4. Slide 4: Board and management

    Board and management Drawn from EBOS/HPS, Baxter and Sandoz — the businesses that already supply Australian hospital pharmacy, with board and management experience across ASX and Nasdaq-listed companies. Leadership David Hainsworth David Gulland Troy Valentine Vishal Shah Waleed Elsayed Executive Ch

  5. Slide 5: AlgoraeRx: commercial subsidiary supplying generic and specialty medicines

    AlgoraeRx · Strategic expansion Our commercial subsidiary, supplying generic and specialty medicines Products sourced from contracted manufacturers, supplied through established Australian and New Zealand channels. 01 02 Generic and specialty medicines across ANZ Addressing unmet local supply needs

  6. Slide 6: Why AlgoraeRx is positioned to succeed

    AlgoraeRx · Positioning Why AlgoraeRx is positioned to succeed AlgoraeRx builds on proven industry expertise rather than creating a pharmaceutical company from the ground up — pairing decades of established relationships and a global manufacturing network with data-led product selection, drawing on

  7. Slide 7: First licence to public-hospital appointment in nine months

    AlgoraeRx · Execution First licence to public-hospital appointment in nine months 6+ Manufacturing partners 25+ Products contracted / MOU 7 Under TGA evaluation 3 Products in market 23 Sep 2025 Nov 2025 – May 2026 Apr – Aug 2026 1 Jul 2026 19 Oct 2026 Q4 CY2026 · Next First licence executed Four fur

  8. Slide 8: Key manufacturing partners

    AlgoraeRx · Execution Key manufacturing partners 6+ manufacturers contracted in just over a year, each producing at scale for global markets. 6+ Manufacturing 25+ Products contracted Categories Oncology Cardiovascular Metabolic Diabetes Mental health Neurology Specialty partners / MOU Partners shown

  9. Slide 9: Two routes to market, the same channels

    AlgoraeRx · Routes to market Two routes to market, the same channels We register products under our own label, and distribute others under the manufacturer’s. Both reach the same hospital, pharmacy and institutional buyers. Licensing / registration Manufacturer’s label Own label Distribution Licence

  10. Slide 10: Market opportunity: Growing demand, fragile supply

    Market opportunity Growing demand, fragile supply Australia’s medicine market is growing fastest in generics — the segment least reliably supplied by offshore manufacturers. Demand The gap The pool A$33bn 432 A$3.43bn market by 2030, from A$24bn in 2025 current shortage reports on the TGA register,

  11. Slide 11: Demand is already concentrated and ageing

    Growth driver 1 of 2 · Population ageing Demand is already concentrated and ageing Australians aged 60 and over fill around 32 PBS prescriptions a head each year, against 6 for everyone else — and they are the fastest-growing part of the population. Today The growth The channel 63% +32% 14.4m of all

  12. Slide 12: Differentiation is how a supplier competes on value

    Growth driver 2 of 2 · Product differentiation Differentiation is how a supplier competes on value Australian generic pricing is among the lowest in the developed world. Formulations and presentations available overseas often never reach Australia — the market is too small to justify a local registr

  13. Slide 13: The team behind AlgoraeOS

    AlgoraeOS · Research and development The team behind AlgoraeOS Combination therapy is foundational in modern oncology, but testing the possible pairings would take millions of experiments. AlgoraeOS predicts which are worth running — developed with UNSW, with validation testing conducted independent

  14. Slide 14: Predict, validate, learn

    AlgoraeOS · Discovery engine Predict, validate, learn AlgoraeOS predicts drug-combination synergy — four metrics at once, at specific doses, with a confidence score on every prediction. 01 · Predict 02 · Validate 03 · Learn 3,000+ compounds 170+ unique cell lines Predicted combinations tested in the

  15. Slide 15: AOS2 achieved validated synergy hit rate ~2.5x that of AOS1

    AlgoraeOS · Validation & scale-up AOS2 achieved an independently validated synergy hit rate ~2.5× that of AOS1 Three preclinical programs run independently by the Victorian Centre for Functional Genomics at Peter Mac, against the same predefined synergy thresholds — two complete and the third underw

  16. Slide 16: Preclinical pipeline

    AlgoraeOS · Preclinical pipeline Preclinical pipeline Two fixed-dose combination programs, both preclinical and both with IP filed — one with a clinical pathway being scoped, one still generating efficacy and safety data. AI-116 — fixed-dose combination (Dementia) AI-168 — fixed-dose combination (Ca

  17. Slide 17: Corporate overview

    Corporate Corporate overview Capital structure and register. Market cap Cash EV $18.2m − $3.15m = $15.1m 2.02bn shares × $0.009 30 Sep 2026, unaudited Enterprise value Securities Funding Register composition As at 6 Oct 2026 ASX code 1AI Cash $3.15m Top 40 holders 30 Sep 2026, unaudited Shares on is

  18. Slide 18: What happens next

    Outlook · Both engines What happens next Near-term revenue Longer-dated optionality AlgoraeRx AlgoraeOS Underway Revenue generation from products in market. Underway Third program with Peter Mac to independently validate predictions generated by the AOS2 multi-anchor program. Expected Q4 CY2026 As t

  19. Slide 19: Contacts

    Contacts Two engines. Independent validation. Commercial execution underway. Corporate & Media Enquiries [email protected] Website algoraepharma.com ASX Announcements algoraepharma.com/investors/announcements Corporate Address Level 23, Rialto South Tower 525 Collins St, Melbourne VIC 3000

  20. Slide 20: References

    Appendix References Full sources, table references, retrieval dates and calculation methods for the figures used throughout this presentation. Pages 5 and 10 Medicine shortages Pages 5 and 10 Pool TGA Medicine Shortage Reports Database, shortage status “Current” — 432 reports covering 218 PBS Expend

  21. Slide 21: References (continued)

    Appendix References (continued) Page 11 PBS age distribution Page 14 AlgoraeOS preprint and benchmarking PBS Expenditure and Prescriptions Report, 1 July 2024 – 30 June 2025 — prescriptions to patients Heydari MJ, Lye B, Masouri P, Marsland T, Pamulapati K, Vary R, Allen H, Simpson KJ, Lock JG, aged

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