Yield10 Bioscience, Inc. · OTC:YTENQ

Yield10 Bioscience — IPO Roadshow (October 2019)

26 slides from Yield10 Bioscience's IPO roadshow presentation, Oct 25, 2019

  1. Slide 1: Yield10 Bioscience Investor Presentation

    Yield10 Bioscience, Inc. (NASDAQCM:YTEN) Filed Pursuant to Rule 433 Reg. Statement No. 333-233683 Investor Presentation October 11, 2019 Yield10, an Agricultural Bioscience Company using its “Trait Factory” to Develop High Value Seed Traits for the Agriculture and Food Industries Today October 25, 2

  2. Slide 2: Safe Harbor Statement

    Safe Harbor Statement* The statements made by Yield10 Bioscience, Inc. (the “Company,” “we,” “our” or “us”) herein regarding the Company and its business may be forward-looking in nature and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forw

  3. Slide 3: Free Writing Prospectus

    Free Writing Prospectus This presentation highlights basic information about us and the offering.Because it is a summary that has been prepared solely for informational purposes, it does not contain all of the information that you should consider before investing in our company.Except as otherwise i

  4. Slide 4: Yield10 Bioscience: An Agricultural Bioscience Company

    Yield10 Bioscience (NASDAQ: YTEN) An Agricultural Bioscience Company which uses its “Trait Factory” to Develop High Value Seed Traits for the Agriculture and Food Industries Strong leadership and R&D team (Boston, USA and Saskatoon, Canada) TRAIT FACTORY Performance traits for major crops and specia

  5. Slide 5: Near-term Milestones

    Near-term Milestones Corporate and R&D Milestones Period Completed • Initiate early development program in corn to evaluate novel traits Jan 2019  • Raise $2.9 million Registered Direct Offering – Common Stock only, At-Market Pricing Mar 2019  • Exclusive worldwide license with University of Misso

  6. Slide 6: Yield10 Additional Upcoming Milestones

    Yield10 Additional Upcoming Milestones Yield10 is working to advance our crop technologies and form collaborations • Performance Traits • Expand trait licensing to additional Ag majors to maximize acreage for yield traits • Support Bayer, Forage Genetics, Simplot and other Ag majors in their develop

  7. Slide 7: Path to Commercialization

    Path to Commercialization Today

  8. Slide 8: Trait Factory – Products and Path to Revenue

    Trait Factory – Products and Path to Revenue The “Trait Factory” leverages 26 years of Technology investment/achievements Platform Products Path to Market & Partners Revenue Revenue Model Potential R&D Services, Funded R&D agreements Trait Factory future future $1-6 million Trait gene discovery Mile

  9. Slide 9: Trait Progression to Revenue Generation

    Trait Progression to Revenue Generation GRAIN Platform has produced a rich portfolio of performance traits and enables product opportunities Crop/Trait 2018 2019 2020 - 2022 Canola C3003 11% seed yield increase (field) Canola C3004 Canola Edited oil traits Camelina C3004 26-65% seed yield increase (

  10. Slide 10: Trait Progression – Partner Activities

    Trait Progression – Partner Activities Working with Ag Majors to maximize addressable acreage for performance traits Crop/Trait Partner Agreement 2018 - 2021 Soybean/C3003 Bayer Research License C3003 Development Soybean/C3004 Global leader in soybean Collaboration biotech trait development C3004 an

  11. Slide 11: Rich Pipeline of Trait Genes in Development

    Yield10: Rich Pipeline of Trait Genes in Development Many opportunities exist for licensing and/or partnerships Potential Acres Annual Revenue Traits Target Crops (N. America) Potential Seed yield C3003, C3004 canola, soybean1, corn, 200 million $1-3 billion Oil content – focus on genome editing tar

  12. Slide 12: Licensing Revenue Model

    Licensing Revenue Model Traits can be deployed using traditional genetic engineering or genome editing tools Licensing revenue model – canola example Regulated Trait (4-8 years) Costs Genome edited trait (3-5 years) Time 1. http://www.statcan.ga.ca/daily-quotidien/161206/dq161206b-eng.htm, AAFC proj

  13. Slide 13: Camelina Platform Market Opportunity & Development

    Camelina Platform Market Opportunity & Development Today

  14. Slide 14: Camelina Products – Market Development Strategy

    Camelina Products – Market Development Strategy PHA Biomaterials – plastic resin grade • Low cost PHA raw material supplier • Empower consumer packaging innovators (App developers) to create consumer solutions with PHA biomaterials Product volume & PHA Biomaterials - water treatment grade revenue •

  15. Slide 15: A Compelling Market Opportunity

    A Compelling Market Opportunity Yield10 develops high value performance traits and specialty crop products Efficiently developing performance and product traits for major crops Global Food and Ag is a ~ $5 trillion market today Milling/Food Manufacturers | Seed Co | Farmers | Supermarket Food produc

  16. Slide 16: Nutrient Run-Off Impacts Human Health and the Environment

    Nutrient Run-Off Impacts Human Health and the Environment Human health “Considering all studies, the strongest evidence for a relationship between drinking water nitrate ingestion and adverse health outcomes (besides methemoglobinemia) is for colorectal cancer, thyroid disease, and neural tube defec

  17. Slide 17: Cash Cover Crops – The Camelina Platform

    Cash Cover Crops – The Camelina Platform The oilseed Camelina has large acre potential as a cash cover crop • Cover crops can be planted after the main crop harvest • A second crop from the same land increases productivity • Cash cover crops can increase farm revenue and reduce nutrient run-off • En

  18. Slide 18: Camelina Platform for Producing PHA Biomaterials

    Camelina Platform for Producing PHA Biomaterials Yield10 has made significant progress in achieving plant-based production of the simplest member of the natural PHA biopolymer family Problem PHA Biomaterial Market Opportunity Water nutrient pollution • PHA a natural biodegradable product for (nitrat

  19. Slide 19: Production of PHA in Oilseeds

    Production of Polyhydroxyalkanoate (PHA) in Oilseeds PHA cash cover crop: Harnessing nature to heal nature Cash cover crop mitigates nutrient runoff in field, produces PHA biomaterial product for water treatment Camelina based PHA biomaterials value delivery chain Winter cover crop Camelina engineer

  20. Slide 20: Clean Water: PHA Water Treatment Applications

    Clean Water: PHA Water Treatment Applications • PHA is a natural part of the carbon/nitrogen cycle in water treatment facilities • A PHA nitrate removal system is self-regulating, requires minimum maintenance Denitrifying bacteria Denitrifying bacteria Bacteria consume PHA and convert nitrate to nit

  21. Slide 21: Capitalization & Executive Team

    Capitalization & Executive Team Today

  22. Slide 22: Capitalization Table

    Capitalization Table Ownership Table as of October 2, 2019 Holder # of Common Shares % of Common Shares Jack Schuler 3,804,885 30.3% Officers and Directors as a group 243,590 1.9% Public Float 8,519,107 67.8% Total Common Shares Outstanding 12,567,582 100.0% Capitalization Table as of October 2, 201

  23. Slide 23: Executive Team

    Executive Team Oliver Peoples, Ph.D. Dr. Peoples is a pioneer of the field of metabolic engineering, the forerunner of synthetic biology, which began at MIT in the mid 1980’s and an experienced entrepreneur and biotechnology executive with over 35 President & CEO, years of experience in science and

  24. Slide 24: Board of Directors (non-executive)

    Board of Directors (non-executive) Robert Van Nostrand Chairman of the Board since October 2013, Director since 2006. Spent 21 years with OSI Pharmaceuticals Chairman where he held various roles including CFO. Prof. Anthony Sinskey, Director since June 1992, a co-founder of Metabolix, Inc. MIT facul

  25. Slide 25: Yield10 Bioscience: An Agricultural Bioscience Company

    Yield10 Bioscience (NASDAQ: YTEN) An Agricultural Bioscience Company which uses its “Trait Factory” to Develop High Value Seed Traits for the Agriculture and Food Industries Strong leadership and R&D team (Boston, USA and Saskatoon, Canada) TRAIT FACTORY Performance traits for major crops and specia

  26. Slide 26: Yield10 Bioscience, Inc. (NASDAQCM:YTEN)

    Yield10 Bioscience, Inc. (NASDAQCM:YTEN) Investor Presentation Yield10, an Agricultural Bioscience Company using its “Trait Factory” to Develop High Value Seed Traits for the Agriculture and Food Industries Today October 25, 2019

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