Neurizon Therapeutics Limited · ASX:NUZ
Neurizon Therapeutics — Epichem — Investor Presentation (July 2020)
27 slides from Neurizon Therapeutics's investor presentation, July 2020
Slide 1: Corporate Presentation 2020
CORPORATE PRESENTATION 2020 1
Slide 2: A Passion for Chemistry
A PASSION FOR CHEMISTRY HELPING OTHERS SUCCEED Founded in 2003. Chemistry is our Business. Strong Team of PhD-qualified Chemists. State-of-the-Art and Purpose-Built Laboratories. Australian-Based Contract Research Organisation. Registered Research Service Provider. 2
Slide 3: Molecules Made to Order
MOLECULES MADE TO ORDER DRUGS BY DESIGN Our Australian Chemistry Team are Expert Service Providers for: Synthetic & Medicinal Chemistry. Pharmaceutical Reference Materials. Custom Synthesis. Analytical Chemistry. Technical Problem Solving. 3
Slide 4: Australia's Premier Chemistry Business
Technical Experts Registered Research Agency. Certified to ISO 9001. Accredited to ISO 17025 and 17034. AUSTRALIA’S PREMIER Innovative Problem Solvers Top Australian employer of PhD graduates. CHEMISTRY 16 years success helping clients worldwide. BUSINESS Australian Based Export Leader National and
Slide 5: Vision, Mission & Values
Vision To be the Chemistry Provider of Choice offering the most Complete Suite of Organic Chemistry Services and Products. Mission To deliver world-class, innovative and high quality Chemistry VISION, solutions, utilising our expertise and capability in Medicinal, Synthetic Organic and Analytical Ch
Slide 6: Our Valuable Team
OUR VALUABLE TEAM Chief Executive Officer (CEO) Chief Scientific Officer (CSO) Head of Production Head of Quality Head of Analytical Services Head of Corporate Services Project Leaders PhD Chemists Synthetic Organic Chemistry Experts Dedicated Functional Support ▪ Finance and Procurement, Facilities
Slide 7: Meet Our Leadership Team
Dr Martine Keenan Dr James Rixson Chief Scientific Officer Head of Production Colin La Galia Chief Executive Officer Lauren Nieuwpoort Boon Tan Head of Corporate Services Head of Quality MEET OUR LEADERSHIP TEAM
Slide 8: Meet Our Leadership Team
MEET OUR LEADERSHIP TEAM Colin La Galia, Chief Executive Officer Qualifications in Pharmaceutical Manufacturing, Project Management, Human Resources and Business Administration. 30 years’ senior executive experience in Pharmaceutical, Diagnostics and Global Healthcare. Experience includes Abbott Rap
Slide 9: Medicinal Chemistry Expertise
MEDICINAL CHEMISTRY EXPERTISE Medicinal Chemistry & Drug Discovery Proven Track Record of Success Hit-to-Lead projects. Experienced synthetic and medicinal chemists ▪ PhD qualification Lead optimisation towards candidate selection. ▪ Multinational biotechnology experience ▪ CROs Synthesis of analogu
Slide 10: Your Projects. Collaborating. Value Adding.
YOUR PROJECTS. COLLABORATING. VALUE ADDING. Synthetic Chemistry Medicinal Chemistry Project Integration From Client List of Compounds From Client Lead Molecule Request From Client Discovery Program Efficient analogue preparation. Explore optimisation. Develop medicinal chemistry strategy in partners
Slide 11: Our Quality Accreditation
Our Quality Accreditation Epichem’s ISO Quality Accreditation is a Certification system of quality control and quality assurance through the implementation of procedures that are assessed and accredited by an independent body. ISO-9001 ISO-17034 ISO-17025 ▪ Requirement for a QMS, including documenta
Slide 12: Our Facilities
OUR FACILITIES Laboratories Epichem maintains some of the best equipped laboratories in the Southern Hemisphere for the synthesis of drug analogues and other small organic molecules. Leading-edge technology for organic synthesis on a milligram to multigram scale. Quality certification to ISO 9001 an
Slide 13: Reference Materials
REFERENCE MATERIALS MADE IN AUSTRALIA Reference Standard Catalogue Range of rare standards unique to Epichem. Catalogue of impurities, degradants, metabolites of APIs & excipients. ISO 17034 Accreditation Comprehensive Product Information Sheet. Products maintained in stock. Shipped world-wide with
Slide 14: Fine Chemicals and Technical Services
FINE CHEMICALS AND TECHNICAL SERVICES Custom synthesis of single molecules. Impurities, degradants and metabolites of APIs & excipients as custom reference materials. Deuterated and 13C labelled molecules, including metabolites for identification. Isolation, identification and synthesis of impuritie
Slide 15: Analytical Services
ANALYTICAL SERVICES Routine analysis and technical support. Accurate data generation. Rapid data turnaround. Analytical methods validated against published international standards. Expert technical support to resolve your analysis needs. Outstanding client feedback.
Slide 16: Chemistry Services Business Model
CHEMISTRY SERVICES BUSINESS MODEL • Medicinal Chemistry. • Hit Assessment, Lead Generation or Optimisation. • Synthetic Chemistry. • Scaffolds, Intermediates, Analogues, Building Blocks. • Metabolites, Impurities, Reference Compounds. • Pharmaceutical Reference Standards. • Analytical Chemistry. • L
Slide 17: Chemistry Skills
Types of Chemistries Areas of Expertise Reactions & Reagents Heterocyclic, polar, bicyclic synthesis. Synthetic Organic Chemistry. e.g. Peptides and Bioconjugates. Medicinal Chemistry. Hazardous Chemistry: Carbohydrates. Library Design and Optimisation. ▪ Nitration, Material Science. Computational C
Slide 18: Our Scientific Process: Design and Synthesis
OUR SCIENTIFIC PROCESS DESIGN AND SYNTHESIS We are committed to understanding the client’s objectives. Design the most efficient route based on literature and experience. Time-sensitive. Cost-effective. Eco- and process friendly services.
Slide 19: Our Scientific Process: Characterizations & Deliverables
OUR SCIENTIFIC PROCESS CHARACTERIZATIONS & DELIVERABLES • Final compounds will be characterized by complete spectral data such as 1H NMR, HPLC or LC-MS. • All intermediates are characterized by either LCMS or 1H NMR. • 99% HPLC Purity (in general), 95-98%/>98% for specific compounds. Purity is drive
Slide 20: Our Scientific Process: Delivery and Commitment
OUR SCIENTIFIC PROCESS DELIVERY AND COMMITMENT TIMELINES Track record of accurate projected timelines for Literature reported compounds. Projected timelines for Exploratory compounds. QUALITY Highly committed to providing services that exceed client’s expectations with required quality. Focusing on
Slide 21: Management & Communication by Project Leader
MANAGEMENT & COMMUNICATION BY PROJECT LEADER Project Leader is the single point of contact for each client. Each project assigned a unique project code. Regular phone, video calls and emails as per client’s specifications. Project planning in partnership with Bench Chemists. Daily follow up, analysi
Slide 22: Procurement & Logistics
PROCUREMENT & 85% of 10-15% Chemicals Chemicals LOGISTICS Delivered Delivered CHEMICAL 3-5 Days 6-8 days PROCUREMENT Unavailable key starting materials synthesized in-house Same-day dispatch from major vendors. Rare Materials Local 14-20 Days 24-48 Hours Periodic review of key vendors. Fasttrack at
Slide 23: IP Protection & Confidentiality
IP PROTECTION & CONFIDENTIALITY IP Intellectual Property Outcome of client projects at our laboratories belongs entirely to our client. Epichem will transfer IP. Confidentiality Each project under a given client is tracked by a unique code. Project codes are used for raw material purchase, analytica
Slide 24: Our Beliefs
OUR BELIEFS Reliability and Integrity quality, confidentiality and timeliness Customer Commitment delivering the highest standards Valuing our People success is based on the strength of our team Innovation track record of successful client projects Cost and Competition exceptional value for money an
Slide 25: Our Awards
OUR AWARDS 2020 GHP Biotechnology Most Innovative Australian Chemistry Service Provider and Best in Organic Chemistry Solutions. 2019 Epichem wins the International Health Award at the WA Industry and Export Awards. 2019 Chief Scientific Officer, Dr Martine Keenan, is awarded Fellowship to the Royal
Slide 26: Testimonials
TESTIMONIALS “Prompt and expert response “Mr Tan was very helpful with after enquiry, quick packing short turnaround times and and delivery, and competitive “They provide great service, not just a small sample sizes. He made price. In particular, we liked the great product. Epichem stands behind the
Slide 27: Contact Us
CONTACT US Colin La Galia, CEO [email protected] +61 (8) 6167 5200 / 5205 www.epichem.com.au