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Neurotech International — European Neuro Convention 2017
32 slides from Neurotech International's conference presentation, Jun 8, 2017
Slide 1: 2017 European Neuro Convention Presentation
2017 European Neuro Convention Presentation For personal use only Perth, Australia & Malta – 8 June 2017 – Please find enclosed the presentation accompanying a keynote speech delivered by Dr Adrian Attard Trevisan, at the European Neuro Convention in London yesterday. Dr Attard Trevisan is the found
Slide 2: EEG Driven Therapies in the field of Autism and Intellectual Disabilities
For personal use only EEG Driven Therapies: in the field of Autism and Intellectual Disabilities Dr Adrian Attard Trevisan, Ph.D Founder / Scientific Advisor - Neurotech International Research Fellow – BMHR-CU Date: 2017/06/07
Slide 3: Contents
Contents: For personal use only • Introduction about Electroencephalography (EEG) and Entrainment • EEG abnormalities in Autism • Use of Neurofeedback to treat ASD • Mente Autism – Neurofeedback for ASD 2 EEG Driven Therapies: in the field of Autism and Intellectual Disabilities| 2017/06/07
Slide 4: Introduction about EEG and Entrainment
For personal use only Introduction about Electroencephalography (EEG) and Entrainment
Slide 5: Introduction
Introduction For personal use only Hans Berger (1929) already believed that abnormalities in EEG reflect clinical disorders. In a large variety of psychiatric disorders or psychological diseases, indeed, several abnormalities in the brainwave activity can be observed, often related to alterations in
Slide 6: Introduction: EEG entrainment
Introduction For personal use only In 1934, Adrian and Matthews showed, through their results, that the alpha rhythm could be “driven” above and below its natural frequency with photic stimulation (Adrian & Matthews, 1934). EEG entrainment Brain tends to follow and produce specific frequencies, with
Slide 7: How can EEG entrainment be promoted?
How can EEG entrainment be promoted ? For personal use only Visual or photic Stimulation Auditory or binaural beats Photic stimulation: AudioVisual flickering or flashing Stimulation (AVE) light where the more sophisticated is the stimulus the greater effect on endogenous rhythms. Binaural beats: tw
Slide 8: What kind of brain waves are best to be entrained?
What kind of Brain waves are the best to be entrained? For personal use only • Delta: useful to relax and to promote sleep • Theta: relaxation • Alpha: best entrainment • Beta: best for ADHD The collection of evidences from several studies pointed out a specific pattern named “EEG slowing” character
Slide 9: QEEG
QEEG For personal use only • Quantitative EEG is a clinical diagnostic tool, which measures brain dysfunction and activity. It points to areas of dysfunction, quantifying specific abnormalities and assists in the differential diagnosis process. Unlike other testing, such as MRI, CAT Scan, FMRI, and
Slide 10: EEG abnormalities in Autism
For personal use only EEG abnormalities in Autism
Slide 11: ASD and EEG abnormalities
ASD and EEG abnormalities For personal use only The aim of neurofeedback treatment in children and adolescents with ASD has been on normalizing abnormalities in: • EEG power spectra (Jarusiewicz, 2002; Scolnick, 2005; Sichel et al., 1995), • connectivity (Coben & Padolsky, 2007), and • the mirror ne
Slide 12: EEG power bands in children with ASD
EEG power bands in children with ASD For personal use only Resting-state EEG studies of ASD suggest a U- shaped profile of electrophysiological power alterations, with excessive power in low-frequency (delta and theta) and high-frequency bands (beta and gamma), but reduced power in the middle- range
Slide 13: High Delta and Theta
High Delta and Theta For personal use only A constant pattern in ASD has emerged showing excessive power at low-frequency delta and theta and high frequency (beta, gamma) bands; but reduced power in the middle-range frequency band alpha has been found in children at all stages of development (Cantor
Slide 14: High Delta in ASD
High Delta in ASD For personal use only Spectrum analyses revealed that children with ASD showed significantly less relative alpha and more relative delta than normal control subjects. (Chan et al., 2007) The only between-group difference in absolute EEG Spectral Power was a higher amount of prefron
Slide 15: High Theta in ASD
High Theta in ASD For personal use only • Pop-Jordanova, N., Zorcec, T., Demerdzieva, A., & Gucev, Z. (2010). QEEG characteristics and spectrum weighted frequency for children diagnosed as autistic spectrum disorder. Nonlinear Biomedical Physics, 4, 4. • Daoust, A. M., Limoges, Elyse, Bolduc, C., Mo
Slide 16: Abnormalities in connectivity & coherence
Abnormalities in connectivity & coherence For personal use only A study by Murias et al. (2007) explored the fact that theoretical conceptions of autism spectrum disorder (ASD) and experimental studies of cerebral blood flow suggest abnormalities in connections among distributed neural systems in AS
Slide 17: Abnormalities in connectivity & coherence
Abnormalities in connectivity & coherence For personal use only Robust patterns of over- and under-connectivity are apparent at distinct spatial and temporal scales in ASD subjects in the eyes closed resting state. In the lower alpha range (8-10 Hz), globally reduced coherence was evident for the AS
Slide 18: Abnormalities in connectivity & coherence
Abnormalities in connectivity & coherence For personal use only A study conducted by Coben et al. in 2008 explored the difference between a control group and a group with ASD in terms of connectivity and coherence. There were group differences in power, intrahemispheric and interhemispheric coherenc
Slide 19: ASD and Delta and Theta Coherence
ASD and Delta and Theta Coherence For personal use only • Coben, R., Clarke, A. R., Hudspeth, W., & Barry, R. J. (2008). EEG power and coherence in autistic spectrum disorder. Clinical Neurophysiology, 119(5), 1002–1009. • Barttfeld, P., Wicker, B., Cukier, S., Navarta, S., Lew, S., & Sigman, M. (20
Slide 20: Use of Neurofeedback to treat ASD
For personal use only Use of Neurofeedback to treat ASD
Slide 21: Use of Neurofeedback to treat ASD
Use of Neurofeedback to treat ASD For personal use only In a study published by Kouijzer (2009), subjects with ASD underwent Neurofeedback training aimed at reducing theta activity (4-7Hz) while increasing activity in the low beta band (12-15Hz). Results showed a significant reduction of theta power
Slide 22: Use of Neurofeedback to treat ASD
Use of Neurofeedback to treat ASD For personal use only Average theta (4–7 Hz) power during neurofeedback sessions recorded over C3 (left graph) and C4 (right graph) indicating the reduction in theta power over consecutive sessions. Regression lines reflect the slope of theta reduction over time for
Slide 23: Use of Neurofeedback to treat ASD
Use of Neurofeedback to treat ASD For personal use only Average delta (1.3–3.5 Hz) power during neurofeedback sessions recorded over C3 (left graph) and C4 (right graph) indicating the reduction in delta power over consecutive sessions. Regression lines reflect the slope of delta reduction over time
Slide 24: Use of Neurofeedback to treat ASD
Use of Neurofeedback to treat ASD For personal use only • Kouijzer conducted a trial in which seven out of 13 participants of the EEG-biofeedback group successfully reduced delta and theta power and were named as EEG-responders. EEG- responders furthermore showed a long term improvement in cognitive
Slide 25: Mente Autism – Neurofeedback for ASD
For personal use only Mente Autism – Neurofeedback for ASD
Slide 26: Mente Autism – Neurofeedback for ASD
Mente Autism – Neurofeedback for ASD For personal use only Mente Autism sessions aim to lower the theta/beta and delta/beta ratios. Wang et al. shows that by lowering the theta/beta ratios at the prefrontal site, there was a significant reduction in lethargy and social withdrawal in the patients. Th
Slide 27: Our Idea to help children on the Autism Spectrum
Our Idea to help children on the Autism Spectrum Mente Autism - The science under the hood For personal use only Mente Autism presents the user with a mixture of warble tones and binaural beats that are tailor-made using a set of generative rules with the brain activity levels derived from the user.
Slide 28: Mente Autism - The science under the hood
Our Idea to help children on the Autism Spectrum Mente Autism - The science under the hood For personal use only With its sonified neurofeedback, Mente Autism affects the auditory cortex, which is very close to the thalamus, and stimulates it into reducing delta and theta activity while stabilizing
Slide 29: Why choose sonified neurofeedback?
Our Idea to help children on the Autism Spectrum Mente Autism - The science under the hood For personal use only Why choose sonified neurofeedback? Auditory stimulation Visual stimulation • No registered side effects on • Can induce seizures on ASD auditory stimulation neuro- patients feedback • No
Slide 30: Mente Autism product and QEEG prescription
Our Idea to help children on the Autism Spectrum Mente Autism - The science under the hood For personal use only Product Prescription is purely done on a QEEG test. 29 EEG Driven Therapies: in the field of Autism and Intellectual Disabilities| 2017/06/07
Slide 31: Validation: CE certification and clinical trial
Our Idea to help children on the Autism Spectrum Mente Autism - The science under the hood For personal use only Validation: CE Medical Certification for the product has been achieved An Independent, double blinded , randomized clinical trial is currently underway in USA , more information on : http
Slide 32: Thank you
For personal use only Thank you.
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