Codexis, Inc. · NASDAQ:CDXS
Codexis — Investor Presentation (March 2013)
11 slides from Codexis's investor presentation, March 2013
Slide 1: CodeXyme Cellulase: Groundbreaking New Cellulase for Biofuels and Bio-based Chemicals
CodeXyme® Cellulase: Groundbreaking New Cellulase for Biofuels and Bio-based Chemicals March 2013
Slide 2: Forward-Looking Statements
Forward‐Looking Statements These slides and the accompanying oral presentation contain forward‐looking statements that involve risks and uncertainties. These statements relate to future events or our future financial or operational performance and involve known and unknown risks, uncertainties and o
Slide 3: About Codexis
About Codexis Codexis develops engineered enzymes for pharmaceutical, biofuel and chemical production Biocatalytic solutions to meet customer needs Proven technologies for scale‐up and implementation Rapid, cost‐effective and green process development, integrated from research to manufacturing
Slide 4: Cellulosic Sugar Market Drivers
Cellulosic Sugar Market Drivers Several factors underlie the transition to cellulosic sugars, part of which will be lower cost cellulases Market Drivers Codexis Solution Food vs. Fuel Debate Government Policy • Enzymes for cellulosic Population & Prosperity Growth biofuels and bio-based chemicals Ri
Slide 5: CodeXyme Cellulase: Place in the Value Chain
CodeXyme® Cellulase: Place in the Value Chain Cellulosic Sugar Value Chain Sugar – C5/C6 Pretreatment Saccharification Sugarcane Sugarcane Corn Stover Wheat Rice Bagasse Leaves & Cobs Straw Straw • Cellulase enzymes are the key component in the Proprietary ENZYMES production of cellulosic sugars tha
Slide 6: CodeXyme Cellulase Overview
CodeXyme® Cellulase Overview ® Flexibility Performance Manufacturing Cost CodeXyme® cellulase allows Performance is among the Expect lowest cost‐in‐use for feedstock and best enzyme packages pretreatment flexibility Lower manufacturing cost Higher biomass sugar with onsite plant model Best‐in‐
Slide 7: Progress in CodeXyme Cellulase
Progress in CodeXyme® Cellulase Codexis has delivered significant improvements in enzyme performance and manufacturing cost • Increased enzyme activity: Better hydrolysis • Decreased enzyme cost: Better strains and process performance at commercial loads improved manufacturing process Improvement in
Slide 8: 2012 Enzyme Performance Comparison – NREL
2012 Enzyme Performance Comparison – NREL CodeXyme® 3 was effective in process‐relevant conditions C6 Conversion @ 30 mg enzyme / g glucan (whole slurry) 100 100 • NREL concluded that CodeXyme® 3 can effectively hydrolyze dilute‐acid pretreated % C6 Sugar Conversion 80 80 corn stover cellulose under
Slide 9: 2013 Enzyme Performance Comparison
2013 Enzyme Performance Comparison CodeXyme®4 performs better than competitors’ current (2013) commercial enzyme packages • A third‐party bench‐scale hydrolysis study commissioned by Codexis in 2013 compared CodeXyme®4 versus currently‐available competitor enzyme packages (Enzyme 1 and Enzyme 2, una
Slide 10: Performance Across Feedstocks
Performance Across Feedstocks CodeXyme® cellulase performs well at low enzyme loads (0.8% ‐ 1.6%) and high biomass solids loads across a range of feedstock, resulting in significant flexibility for customers. Flexibility Across Feedstock 100 90 Corn Stover 80 70 Bagasse % C6 Conversion 60 50 Wheat S
Slide 11: Use in Integrated Bio-based Chemical Process
CodeXyme® Use in Integrated Bio‐based Chemical Process CodeXyme® 4X cellulase will be produced at commercially scale in 2Q’13 and used in pilot production of CodeXolTM detergent alcohol in mid‐2013 BIOMASS PRETREATMENT SACCHARIFICATION CELLULOSIC FERMENTATION CODEXOLTM SUGAR DETERGENT ALCOHOL Viscos