Smith & Nephew Plc · LSE:SN.
Smith & Nephew — Technical Presentation (September 2010)
18 slides from Smith & Nephew's technical presentation, Sep 21, 2010
Slide 1: Confidential – Do Not Distribute
Confidential – Do Not Distribute
Slide 2: LEGION to GENESIS II Comparison
LEGION™ to GENESIS™ II Comparison September 21, 2010 Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 3: A legacy of innovation and success
A legacy of innovation and success GENESIS™ II GENESIS II GENESIS II LEGION™ LEGION VERILAST™ LEGION W/OXINIUM™ SPC REVISION CR and PS Technology Porous CR (Re-branded GII SPC) 1995 1997 2005 2008 2009 Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly
Slide 4: LEGION and GENESIS II claims
GENESIS™ II CR GENESIS II PS LEGION CR LEGION PS LEGION CK Cruciate Retaining Knee Posterior Stablized Knee Cruciate Retaining Knee Posterior Stabilized Knee Constrained Knee Built-in Femoral Rotation Surgeon-directed Femoral Rotation Compatible Base Plates, Inserts, Patellas, Augments, Stems and Of
Slide 5: Rotating sizing guide usage on left knee
Rotating sizing guide usage on left knee M L M L Drill holes for DCF block Guide set @3 Guide set @0 for LEGION™ for GENESIS™ II Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trad
Slide 6: DCF cutting block placement
DCF cutting block placement LEGION™ GENESIS™ II M L M L 12mm 9.5mm 9.5mm Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 7: After bone cuts
After bone cuts LEGION™ GENESIS™ II M L M L Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 8: Implantation
Implantation LEGION™ GENESIS™ II M L M L 9.5mm 7mm 9.5mm Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 9: Results in identical flexion space
Results in identical flexion space LEGION™ GENESIS™ II M L M L Original post. Condylar ref line Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 10: Performance comparison LEGION and GENESIS II
Performance comparison LEGION™ and GENESIS™ II Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 11: Software overview
Software overview • Dynamic simulation of an Oxford™ Rig • Uses a physics based algorithm to determine kinematics and kinetics • Muscles, soft tissues, implant contact modeled • Deep knee bend and gait Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly
Slide 12: Validation
Validation • Simulation results validated on real world Oxford™ Rig knee simulator – Rullkoetter, P.J., McGuan, S., Maletsky, L.P., “Development and Verification of a Virtual Knee Simulator for TKR Evaluation”, 45th Annual Meeting, ORS, Feb 1-4, 1999, Anaheim California • FDA accepts results from Li
Slide 13: Kansas knee simulator
Kansas knee simulator Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 14: Simulation movie
Simulation movie ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 15: ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
Slide 16: MCL, ITB and IT-Patellar strain performance
GII HFPS MCL Strain 0.2 Legion HFPS 0.18 Performance 0.16 MCL strain (mm/mm) 0.14 0.12 0.1 0.08 0.06 0.04 0.02 0 0 30 60 90 120 150 Knee Flexion (deg) GII HFPS GII HFPS IT-Patellar Strain ITB Strain 0.2 Legion HFPS 0.2 Legion HFPS 0.18 0.18 IT-Patellar strain (mm/mm) 0.16 0.16 ITB strain (mm/mm) 0.1
Slide 17: Patella ML position and performance summary
GII HFPS PF ML (mm) (+med patella) Performance 6 Legion HFPS Patella ML position (mm) 5 4 3 2 Summary 1 • LEGION™ PS and CR both give the 0 same performance as GENESIS™ II -1 0 30 60 90 120 Knee Flexion (deg) 150 with the added benefit of a more -2 -3 lateralized PF groove in extension -4 and gait G
Slide 18: Confidential – For internal use only
Confidential – For internal use only by Smith & Nephew employees and sales force. Do not publicly distribute. ™Trademark of Smith & Nephew. Reg. US Pat. & TM Off. All Trademarks acknowledged.
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