Yield10 Bioscience, Inc. · OTC:YTENQ
Yield10 Bioscience — Investor Presentation (March 2018)
22 slides from Yield10 Bioscience's investor presentation, March 2018
Slide 1: Yield10 Bioscience Investor Presentation
Yield10 Bioscience, Inc. (NASDAQCM:YTEN) Investor Presentation Yield10 is developing new technologies to achieve step-changes in crop yield to enhance global food security Today 2018 March
Slide 2: Safe Harbor Statement
Safe Harbor Statement* The statements made by Yield10 Bioscience, Inc. (the “Company,” “we,” “our” or “us”) herein regarding the Company and its business may be forward-looking in nature and are made pursuant to the safe harbor provisions of the Private Securities Litigation Reform Act of 1995. Forw
Slide 3: Investment Considerations
Investment Considerations “Yield10 designs precise alterations to gene activity in food and feed crops to produce higher yields with lower inputs of land, water or fertilizer” Leverages a large historical investment in advanced metabolic engineering into the Ag space • 15 recent patent applications
Slide 4: Company Overview
Company Overview Yield10 Bioscience (NasdaqCM:YTEN) is developing technologies to enhance global food security • Headquartered in Woburn, MA USA • Oilseeds center of excellence in Saskatoon, Canada Yield10 is bringing extensive expertise and track record in optimizing the flow of carbon in living sy
Slide 5: Leadership Team
Leadership Team • Founder and CSO of Metabolix, an MIT spinout, Dr. Peoples is an experienced entrepreneur and biotechnology Oliver Peoples, Ph.D. executive with over 30 years of experience in science and technology innovation and commercialization CEO • He initiated the crop science program over a
Slide 6: Our Team Achieved all Major Objectives in 2017
Our Team Achieved all Major Objectives in 2017 Kicked off 2017 with renaming and rebranding as Yield10 Bioscience, Inc. Added 2 key scientists and board member with agricultural business experience Conducted Field Tests for C3003 in Camelina and canola Reported encouraging results for C3003
Slide 7: Recent Accomplishments
Recent Accomplishments Granted Research License to Monsanto for Evaluation of C3003 & C3004 in Soybean • Non-exclusive term of approx. 3.5 years, preserves YTEN downstream rights • Contributes significant resources and expertise in soybean research and breeding to YTEN C3003/C3004 yield trait prog
Slide 8: Yield10 is Well Positioned for 2018
Yield10 is Well Positioned for 2018 • Rich pipeline of yield traits in development addresses compelling market opportunity • Deploying R&D resources to generate proof points in key crops • Field tests • Greenhouse studies • USDA-APHIS submissions • Opportunities for licenses and collaborations Today
Slide 9: Yield10: A Compelling Market Opportunity
Yield10: A Compelling Market Opportunity Yield10 is…….Aligned with compelling megatrends 9 October 2009; Revised June, 2015 GA/EF/3242 Food Production Must Double by 2050 Global Food Security…… increasing overall demand and increased protein consumption Health and Wellness.....improved nutrition pro
Slide 10: Commercial Strategy
Commercial Strategy Yield10 Technologies Enable Multiple Paths to Value Creation Driven by Unique Traits and Trait Discovery Capabilities Major North American Commodity Crops Accelerate deployment with Ag majors Provide low hurdle to deploy and test yield traits in elite germplasm License agre
Slide 11: Rich Pipeline of Trait Genes in Development
Rich Pipeline of Trait Genes in Development SUMMARY OF OUR CROP TRAITS IN DEVELOPMENT Business Area Current Status Seed Yield Traits-Regulated Camelina 1st and 2nd generation at field testing stage Many opportunities C3003 Canola 1st generation at field testing stage Soybean and rice in development
Slide 12: Granted Research License to Monsanto
Granted Research License to Monsanto Research license to C3003 and C3004 to improve yield in soybean • Market leader in GM soybean seed in the United States and North America • Non-exclusive term of approx. 3.5 years, preserves YTEN downstream rights • Develop and test C3003 in proprietary soybean l
Slide 13: Value Creation Model: Seed Yield and Oil Content
Value Creation Model: Seed Yield and Oil Content Yield10’s gene traits may enable value creation through step-change increases in crop yield Canola(1) (Can) Soybean(2) (US) Corn(2) (US) An illustrative example of the annual revenue opportunity 2016 Harvest 2016 Harvest 2016 Harvest for Yield10’s can
Slide 14: Novel Yield Trait Gene: C3003
Novel Yield Trait Gene: C3003 C3003 is a component of an algal system for increasing photosynthesis in low CO2 conditions • A scientific discovery from University of Massachusetts with a unique biological mechanism • C3003 improves the metabolic infrastructure of the plants • Potential to be useful
Slide 15: Summary of 2017 Field Test Results
Summary of 2017 Field Test Results Generated Encouraging Results for C3003 in Camelina and Canola Minicage Plots of C3003 Gen 2.0,Gen 2.1 Objectives • Conduct first field test with Gen 2.0 C3003 in Camelina and first field test of Gen 1.0 in Canola • Generate technical data and determine the best wa
Slide 16: Development of C3003 in Soybean
Development of C3003 in Soybean Generated Preliminary Greenhouse Results for Soybean in 2017 Informing Plans for 2018 Current Status and Recent Results • Developed Gen 1 and Gen 2 C3003 constructs/events with academic collaborator in Canada • Preliminary observations from greenhouse grown plants ind
Slide 17: Novel Traits for Boosting Seed Oil Content
Novel Traits for Boosting Seed Oil Content Yield10 is uniquely positioned to re-engineer the oil biosynthesis pathway in oilseed crops Current Status Seed • Boosting oil yield significantly increases the value of the crop to the grower • Discovered and acquired more than 5 targets involved in oil bi
Slide 18: Progressing C4000 Series Traits Generated from T3 Platform
Progressing C4000 Series Traits Generated from T3 Platform Yield10 is uniquely positioned to identify valuable targets based on global transcription factors Current Status • Reported data showing that C4001 boosts key parameter of photosynthesis (~75%) and improves plant biomass (~75-100%) in switch
Slide 19: Deactivation of Transcription Factor Genes (C4004–C4027)
Deactivation of Transcription Factor Genes (C4004 –C4027) The T3 Platform identifies key downstream transcription factors • Focus on down regulated transcription factor genes, 24 in total • C4004 – C4027, simplest targets for genome editing • C4004 is the only transcription factor gene downregulated
Slide 20: Genome Editing in Agriculture
Genome Editing in Agriculture Next Phase of High-Tech Crops, Editing Their Genes (May 7, 2017 By Jacob Bunge) • Genome editing completes the toolbox for enhancing crop yield and value • Genome editing enables Precision Molecular Breeding of gene combinations for enhancing crop yield • Genome edited
Slide 21: Upcoming Milestones
Upcoming Milestones Yield10 is working to advance our crop yield technologies and build collaborations • Continue progress on C3003 with additional constructs and crops • Planning and permitting underway for 2018 field testing of C3003 in Camelina and canola in Canada • Anticipate planting in 2Q 201
Slide 22: Yield10 Bioscience, Inc.
Yield10 Bioscience, Inc. (NASDAQCM:YTEN) Investor Presentation Yield10 is developing new technologies to achieve step-changes in crop yield to enhance global food security Today2018 March
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