Bio-gene Technology Ltd. · ASX:BGT
Bio-gene Technology — Investor Presentation (May 2018)
23 slides from Bio-gene Technology's investor presentation, May 2018
Slide 1: Bio-Gene Technology Company Overview
Bio-Gene Technology Company Overview May 2018 “AN AGTECH DEVELOPMENT COMPANY ENABLING A NEW GENERATION OF NOVEL INSECTICIDES THAT ADDRESS INSECTICIDE RESISTANCE” 1 Not for Distribution
Slide 2: Bio-Gene Snapshot
BIO‐GENE SNAPSHOT Data shows initial products Flavocide™ & Qcide™ can be highly effective for insect management Potentially suitable for commercialisation as multiple target insecticides BETA-TRIKETONES Platform Technology Collaborate with commercial An insecticide Key technology enabling a partners
Slide 3: Executive Summary
EXECUTIVE SUMMARY Novel insecticide Unique (new) mode of action (MoA) identified – alternative chemistry to current incumbent platform leading to new insecticides in a market seeking new products – opportunities in a range of market segments effective products with multiple revenue sources Significa
Slide 4: Board Members & Management
BOARD MEMBERS & MANAGEMENT DON BRUMLEY RICHARD JAGGER PETER MAY Non-Executive Chairman CEO & Managing Director Executive Director, R & D • 25+ years as a senior partner & leader of • 20+ years working in agriculture globally • 20+ years experience in crop protection Ernst & Young – Oceania • Most re
Slide 5: Key Advisors to the Board
KEY ADVISORS TO THE BOARD PROF. CATHERINE HILL NEIL ANDERSON DOUG RATHBONE Purdue University Chemistry & Manufacturing Advisor to the BGT Board BGT Scientific Advisory Consultant Board Member • 40+ years experience in agriculture, • Purdue University, Dept. of • Industrial Chemist most recently as M
Slide 6: Bio-Gene Technology Approach
BIO‐GENE TECHNOLOGY APPROACH BETA-TRIKETONES: PLATFORM TECHNOLOGY Synthetic = Replicable at commercial quantities (SCALABLE) FLAVOCIDETM QCIDETM SYNTHETIC COMPOUND, NATURAL OIL PRODUCT, FLAVESONE TASMANONE CONSUMER ANIMAL HEALTH PUBLIC HEALTH CROP PROTECTION APPLICATIONS Targeted pest/animal Targete
Slide 7: Novel Mode of Action (Example Crop Protection)
NOVEL MODE OF ACTION (EXAMPLE CROP PROTECTION) Taken 8% market share & Still US$1.7B in sales per US$1.4B sales per annum annum today today Group 1 Group 11 Group 17 Group 23 Group 28 ACETYLCHOLINESTERA MICROBIAL MOULTING INHIBITORS OF RYANODINE SE (ACHE) INHIBITORS DISRUPTORS OF DISRUPTOR, DIPTERAN
Slide 8: Large Global, Growing Markets
LARGE GLOBAL, GROWING MARKETS Industry dominated by multi- Consumer Applications national AgChem companies $5.1B Sprays, Baits, Repellants Animal Health $6.0B Livestock, Pets Seeking Safe Novel Solutions to complement off-patent insecticides Crop Protection $16.0B Public Health Food, fibre, $4.0B gr
Slide 9: Segments / Pests
SEGMENTS / PESTS SEGMENT PESTS Ectoparasites (ruminants): cattle tick (Rhipicephalus microplus), buffalo fly Animal health Ectoparasites (companion animals): paralysis tick, fleas Public health Mosquitoes, flies Urban pests Flying pests, cockroaches, ants, other crawling pests Lesser grain borer (Rh
Slide 10: Progress & Goals
PROGRESS & GOALS BGT continues to build a suite of research data across a number of pests and verticals Research Partner Initial Follow Up Commercial Product Legend: Testing Testing Partnership Development Committed Complete Beneficial Arthropods Underway / Agreed Upon Lesser Grain Borer Other Grain
Slide 11: Grain Storage Pests
GRAIN STORAGE PESTS Combination treatments with Flavocide™ shown to control the full spectrum of key pests evaluated, including strains resistant to currently used insecticides Demonstrates the compatibility of Flavocide™ with resistance management strategies currently being used in the grain prot
Slide 12: Green Peach Aphid
GREEN PEACH APHID Control of susceptible and highly resistant strains of Green peach aphid demonstrated Flavocide™ outperforms Pirimicarb (a commonly used insecticide) in control of a highly resistant strain of the pest 12
Slide 13: Toxicology Update
TOXICOLOGY UPDATE FlavocideTM Completed acute toxicity six pack Mutagenicity & carcinogenicity tests completed Chronic toxicity testing – seven day sighting study completed 28 day toxicity study (dermal & oral) commenced Physical/chemical studies completed QcideTM Preliminary toxicit
Slide 14: Growing Intellectual Property
GROWING INTELLECTUAL PROPERTY "METHODS & COMPOSITIONS Key granted patents in key FOR CONTROLLING PESTS" territories covering the use of beta-triketones as insecticides Platform patent family Expiring 2022 Insect/crop combination Insect/animal combination Manufacturing patent families patent families
Slide 15: Adding Value by Improving Flavesone Manufacturing
ADDING VALUE BY IMPROVING FLAVESONE MANUFACTURING Ingredients/ intermediates 2,5,10 & 20kg Keys areas for Existing batches process process shows produced for improvement Time Flavesone is collaborators & (cost reduction highly scalable partners & efficiency): Manufacturing method CSIRO collaboration
Slide 16: Ongoing Improvements in Qcide Production
ONGOING IMPROVEMENTS IN QCIDETM PRODUCTION Improved trees Finalising Improvements Production agreement for in oil Improved agreement tissue culture extraction harvest with farmers / cloning processes program Quality control New collaboration • Provides specific tree production knowledge & programs •
Slide 17: 2018 Goals & Objectives
2018 GOALS & OBJECTIVES Update Communicate with • Introductory * meetings held with 7 international companies to date, with 4 NDAs potential partners already signed. Further meetings planned with additional companies Demonstrate activity of lead • Continued work on significant pests and efficacy on
Slide 18: 2018 Goals & Objectives
2018 GOALS & OBJECTIVES Update Continue to clarify • Next phase * commencing which identifies specific “site” of application within known Mode of Action unique channel • Data generated to support our additional patent applications, which will be Generate data to submitted early July. develop further
Slide 19: Regular News Flow Since Listing
REGULAR NEWS FLOW SINCE LISTING 28/05/2018 Positive Results With FlavocideTM vs. Grain Storage Pests 26/04/2018 Positive Efficacy Test Against Another Major Crop Pest (GPA) 17/04/2018 Manufacturing Project with CSIRO Advances To Stage 3 09/04/2018 Positive Result In Efficacy Test With Major
Slide 20: Corporate Update
CORPORATE UPDATE Numbers Description * Shares on Issue 127,724,471 • Includes all shares both quoted and not quoted Voluntary Escrow Shares 17,097,682 • Shares come out of escrow 30/5/18 Remaining Escrow • Various release dates commencing 28/6/18 through Shares 21,051,299 to 29/11/19 Shares Currentl
Slide 21: Corporate Update
CORPORATE UPDATE Cash held at 31 March 2018 - $7.2 million As per Prospectus and per current plans funds will last well into 2019 (excludes any potential proceeds from Loyalty Options) Some funds have been reallocated from FlavocideTM to QcideTM research Loyalty Options expire 4 December 201
Slide 22: Summary
SUMMARY New insecticide platform chemistry, beta-triketones demonstrating a novel mode of action Enables products Flavocide™ & Qcide™ shown to be effective against insecticide resistant pests Applications across multiple market segments including public health, animal health, consumer products & cro
Slide 23: Bio-Gene Technology Contacts
Bio-Gene Technology Richard Jagger Peter May Roger McPherson CEO Exec. Dir., R&D CFO, Co. Sec. M: +61 418 125 646 M +61 412 251 016 M +61 418 416 237 E: [email protected] [email protected] [email protected] 23
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